| 高秀荣,吉宗珊,于庆智,徐 东,王笑妍.血清γ-谷氨酰转肽酶水平与老年2型糖尿病患者并发急性冠脉综合征的相关性分析[J].,2017,17(12):2271-2274 |
| 血清γ-谷氨酰转肽酶水平与老年2型糖尿病患者并发急性冠脉综合征的相关性分析 |
| Analysis of the Correlation of Serum Levels of Gamma-GGTP with the Elderly Patients with Type 2 Diabetes Mellitus Complicated with Acute Coronary Syndrome |
| 投稿时间：2016-12-22 修订日期：2017-01-12 |
| DOI：10.13241/j.cnki.pmb.2017.12.017 |
| 中文关键词: 血清γ-谷氨酰转肽酶 2型糖尿病 急性冠脉综合征 |
| 英文关键词: Gamma Glutamyl Transpeptidase Diabetes Acute coronary syndrome |
| 基金项目:国家自然科学基金项目（81072392）；哈尔滨市科技局青年科学研究基金项目（RC2015QN004122） |
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| 中文摘要: |
| 摘要 目的：探讨血清γ-谷氨酰转肽酶(GGT)水平与老年2型糖尿病患者并发急性冠脉综合征的相关性。方法：选取2015年10月至2016年10月哈尔滨市第一医院收治的老年患者238例，根据病情分为单纯2型糖尿病组81例(DM组)，单纯急性冠脉综合征组78例(ACS组)，2型糖尿病患者合并急性冠脉综合征79例(DA组)；选取同期来我院体检健康者83例作为对照组(NC组)。比较各组一般情况和血清学指标。结果：①DA组BMI大于NC组、DM组和ACS组，血清GGT、糖化血红蛋白(HbA1C)、低密度脂蛋白胆固醇(LDL-C)水平显著高于NC组、DM组和ACS组，血清总胆固醇(TC)、甘油三酯(TG)水平均高于NC组，高密度脂蛋白胆固醇(HDL-C)水平低于NC组(P<0.05)。②血清GGT水平与TG、LDC-C水平呈正相关(p<0.05)。结论：血清GGT水平升高是老年2型糖尿病患者并发急性冠脉综合征的独立危险因素，及时监测老年2型糖尿病患者GGT水平对预测急性冠脉综合征的发生具有重要意义。 |
| 英文摘要: |
| ABSTRACT Objective: To explore serum gamma GGTP (gamma glutamyl transpeptidase) (GGT) level and in elderly patients with type 2 diabetes mellitus complicated with acute coronary syndrome. Methods: Selection in October 2015 to October 2016, Harbin first hospital treated 238c ases of elderly patients, according to the condition can be divided into simple groups, 81 cases of type 2 diabetes mellitus (DM), simple group, 78 cases of acute coronary syndrome (ACS) group (ACS), in patients with type 2 diabetes complicating acute coronary syndrome in 79 cases (DA); Selected at the same time to the hospital physical examination, 83 cases of healthy subjects as control group (NC group). Comparison between groups in general and serological indexes. Results: 1. DA BMI greater than NC group, DM group and ACS group, serum GGT, glycated hemoglobin (HbA1C), low density lipoprotein cholesterol (LDL - C) were significantly higher than that of the NC group, DM group and ACS group, serum total cholesterol (TC), triglyceride (TG) levels were higher than in NC group, the level of high-density lipoprotein cholesterol (HDL - C) below the NC group (P < 0.05).(2) by the Pearson inspection analysis of GGT and the correlation of various factors, serum GGT serum levels and TG LDC - C levels were positively correlated (p < 0.05). Conclusion: Serum GGT level is higher in elderly patients with type 2 diabetes mellitus complicated by independent risk factor for acute coronary syndrome, timely monitoring of elderly patients with type 2 diabetes GGT level, is of great significance to predict the occurrence of acute coronary syndrome. |
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