文章摘要
姚宏涛,徐 军,任冬弓,郝 燚,吴勤智,李洪亮.HoLEP对良性前列腺增生的疗效及安全性观察[J].,2017,17(8):1537-1539
HoLEP对良性前列腺增生的疗效及安全性观察
The Curative Effect and Safety of the HoLEP in Treatment of BPH
投稿时间:2016-07-19  修订日期:2016-08-10
DOI:10.13241/j.cnki.pmb.2017.08.035
中文关键词: BPH  HoLEP  钬激光  前列腺切除术
英文关键词: BPH  HoLEP  Holmium laser  Resection of the prostate
基金项目:陕西省卫生厅医学联合基金项目(2015211C209)
作者单位E-mail
姚宏涛 陕西省第四人民医院泌尿外科 陕西 西安 710043 2443262532@qq.com 
徐 军 陕西省第四人民医院泌尿外科 陕西 西安 710043  
任冬弓 陕西省第四人民医院泌尿外科 陕西 西安 710043  
郝 燚 陕西省第四人民医院泌尿外科 陕西 西安 710043  
吴勤智 陕西省第四人民医院泌尿外科 陕西 西安 710043  
李洪亮 西安医科大学第二附属医院泌尿外科 陕西 西安 710004  
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中文摘要:
      摘要 目的:探讨以尿道钬激光前列腺剜除术(HoLEP)治疗良性前列腺增生(BPH)的临床疗效和安全性。方法:选取我院102例以HoLEP术治疗的BPH患者的临床资料,分析BPH患者的年龄、切除腺体的大小、手术出血量、手术前后的最大尿流率(Qmax)、最大尿流率时逼尿肌压(Pdet/Qmax)、国际前列腺症状评分表(IPSS)评分和生活质量评分(QOLS)等。再选取我院100例以尿道前列腺电切术(TURP)治疗的BPH患者的临床资料,对比两组患者并发症的发生情况。结果:102例BPH患者的年龄为(71.58±9.74)岁,切除腺体为(84.32±36.39)g,手术出血量为(146±24.68)mL,手术前的最大尿流率(8.37±5.28)mL/s,最大尿流率时逼尿肌压为(72.93±26.49)cm H2O,IPSS评分为(28.8±5.98)分,QOLS评分为(5.8±0.46)分;手术后的最大尿流率(24.77±5.89)mL/s,最大尿流率时逼尿肌压为(42.35±10.37)cm H2O,IPSS评分为(9.4±1.28)分,QOLS评分为(2.8±0.28)分。手术后的Qmax明显升高(P<0.05),而Pdet/Qmax、IPSS评分和QOLS均显著降低(P<0.05)。HoLEP术治疗的BPH患者并发症发生明显低于尿道前列腺电切术(TURP)治疗的患者(P<0.05)。结论:HoLEP是一种安全有效的治疗BPH的微创手术。
英文摘要:
      ABSTRACT Objective: To observe the clinical efficacy and safety of the HoLEP treatment of BPH. Methods: 102 BPH patients with HoLEP clinical data were collected in our hospital. Age of the BPH patients, size of their removal gland, surgical blood loss, as well as the Qmax, the Pdet/ Qmax, IPSS and QOLS before and after operation were analyzed. Then another 100 BPH patients treated with TURP clinical data in our hospital were selected and complications of the patients were compared between the two groups. Results: The age of 102 BPH patients was (71.58±9.74) years. The removal glands of patients was (84.32±36.39)g. The loss of surgical blood was (146±24.68) mL. Before the operation, the Qmax was(8.37±5.28) mL/s, Pdet/ Qmax (72.93±26.49) cm H2O, IPSS (28.8±5.98), and QOLS (5.8±0.46). After the operation, the Qmax of patients was (24.77±5.89) mL/s, Pdet/ Qmax of patients (42.35±10.37) cm H2O, IPSS (9.4±1.28), and QOLS (2.8±0.28), which means that Qmax increased significantly (P<0.05), while Pdet/ Qmax, IPSS score and QOLS were significantly lower (P<0.05). Complications occurred significantly less with BPH patients of HoLEP treatment than that with TURP (P<0.05). Conclusion: HoLEP is a safe and effective minimally invasive surgery in the treatment of BPH.
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