| 郭睿 戴建峰 罗玉明 徐俐 沈虹.内镜下穿孔修补术对肝硬化合并消化道穿孔的疗效分析[J].,2017,17(7):1274-1276 |
| 内镜下穿孔修补术对肝硬化合并消化道穿孔的疗效分析 |
| Effect of Endoscopic Perforation Repair on Patients with Liver CirrhosisComplicated with Gastrointestinal Perforation |
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| DOI： |
| 中文关键词: 内镜下穿孔修补术 肝硬化 消化道穿孔 |
| 英文关键词: Endoscopic perforation repair Liver cirrhosis Gastrointestinal perforation |
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| 中文摘要: |
| 目的：研究内镜下穿孔修补术对肝硬化合并消化道穿孔的临床疗效。方法：选择2010 年1 月～2015 年12 月在我院进行诊
治的肝硬化合并消化道穿孔患者82 例，随机分为观察组和对照组，各41例。观察组给予内镜下穿孔修补术治疗，对照组给予传
统的手术切除治疗。观察两组的术中出血量、手术时间、术后住院时间和术后下床活动时间等围手术期指标；检测两组手术前和
手术后的谷草转氨酶、谷丙转氨酶和酌-谷氨酰转移酶等肝功能指标；观察两组的并发症发生情况和生存情况。结果：观察组的术
后出血量明显少于对照组(P<0.05)，术后住院时间和术后下床活动时间明显短于对照组(P<0.05)；两组治疗后的肝功能指标AST、
ALT、r-GT 水平均比治疗前明显降低(P<0.05)，且观察组治疗后肝功能水平的下降幅度比对照组更为明显(P<0.05)；观察组的并发
症发生率为4.88%(2/41)，明显低于对照组的26.83%(11/41) (P<0.05)；观察组的平均生存时间和1 年生存率均明显高于对照组
(P<0.05)。结论：内镜下穿孔修补术对肝硬化合并消化道穿孔患者手术创伤小，可促进肝功能的恢复，且术后并发症少，从而可改
善患者的远期生存情况。 |
| 英文摘要: |
| Objective:To study the effect of endoscopic perforation repair on patients with liver cirrhosis complicated with gastrointestinal
perforation.Methods:82 cases of patients with liver cirrhosis complicated with gastrointestinal perforation who were treated
in our hospital from January 2012 to December 2015were selected and divided into two groups randomly, 41 cases each group. The observation
group was treated with endoscopic perforation repair, and the control group was treated with traditional surgical resection. The
intraoperative blood loss volume, operative time, postoperative hospital stay and postoperative activity time, AST, ALT, r-GT, complications
and survival of the two groups were compared.Results:The postoperative blood loss volume of observation group was significantly
less than that of control group (P<0.05), and the postoperative hospital stay and postoperative ambulation time was significantly shorter
than that of control group (P<0.05); after treatment, the level of AST, ALT, 酌-GT of the two groups were significantly lower than before
treatment (P<0.05), and these indexes in the observation group were decreased significantly than those of control group (P<0.05); the incidence
of complications of observation group was 4.88%(2/41), significantly lower than 26.83%of the control group (11/41) (P<0.05);
and the average survival time and 1 year survival rateof observation group was significantly higher than that of control group (P<0.05).Conclusion:Endoscopic perforation repair has small surgical trauma for patients with liver cirrhosis complicated with gastrointestinal
perforation, and can promote the recovery of liver function with less postoperative complications, which can improve the long-term survival
situation. |
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