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目的：探讨罗哌卡因复合舒芬太尼在潜伏期分娩镇痛中的应用效果。方法：择取2015 年1月~2016年1 月我院收治的产妇 102例，随机分为A、B、C组，各组34例，A组产妇宫口开至1 cm 时采取罗哌卡因复合舒芬太尼硬膜外自控分娩镇痛，B 组产妇宫口开至3 cm时采取罗哌卡因复合舒芬太尼硬膜外自控分娩镇痛，C 组产妇未采取分娩镇痛，比较两组第一产程潜伏期、活跃期及第二产程持续时间及宫缩时视觉模拟评分（VAS）评分，比较各组产妇出血量、新生儿体质量及胎儿娩出后1 min、5 min Apgar 评分，记录各组治疗30 d 后不良反应。结果：A组、B 组第一产程潜伏期持续时间明显较C 组延长，活跃期持续时间较C 组明显缩短，差异有统计学意义（P<0.05）；A组产妇宫颈口开至2 cm 和cm 时VAS 评分低于B 组和C 组，差异有统计学意义（P<0.05）；A 组、B组产妇在活跃期、第二产程时VAS评分低于C 组，差异有统计学意义（P<0.05）；各组产妇出血量、新生儿体质量、Apgar 评分比较均无统计学意义（P>0.05）；C组抑郁症发生率均高于较A 组和B组，差异有统计学意义（P<0.05）。结论：从产妇潜伏期开始应用罗哌卡因复合舒芬太尼进行分娩镇痛的效果较好，具有良好的应用价值。

英文摘要:

Objective:To investigate the application effect of ropivacaine combined with sufentanil in incubation period labor analgesia.Methods:Selected 102 puerperas treated in our hospital fromJanuary 2015 to January 2016, which were randomly divided into group A, B and C, with 34 cases in each group, the group A was treated with patient controlled epidural analgesia with ropivacaine combined with sufentanil when maternal uterine mouth open to 1 cm, the group B was treated the same analgesia as group A when maternal uterine mouth open to 3 cm, while the group C was not taken any delivery analgesia, then the duration of production and the visual analogue scale(VAS) score at incubation period, active period, the second stage of labor were compared in three groups, as well as compared the maternal bleeding volume, neonatal body mass, and Apgar score 1 min, 5 min after fetal disengagement.Results:The duration of incubation period in group A and B were significantly longer than group C, and the duration of active period in theses two groups was significantly shorter than group C, the differences were statistically significant (P<0.05); The VAS score in group A was lower than group B and group C when the maternal uterine mouth open to 2 cm and 3 cm, the differences were statistically significant (P<0.05); The VAS score in group A and group B were lower than group C at active period, the second stage of labor, the differences were statistically significant (P<0.05); The maternal bleeding volume, neonatal body mass, and Apgar score in each groups was not statistically significant(P>0. 05); The depression occur rate in group C was higher than group A and group B, the differences were statistically significant(P<0.05).Conclusion:Using ropivacaine combined with sufentanil for labor analgesia has good effect from incubation period, which has good application value.

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