| 刘瑶 陈曦 刘娟 薛艳明 王京华△.骨髓增生异常综合征合并非霍奇金淋巴瘤一例病例报道并文献复习[J].,2016,16(27):5321-5323 |
| 骨髓增生异常综合征合并非霍奇金淋巴瘤一例病例报道并文献复习 |
| A Case Report of Myelodysplastic Syndrome with Non-Hodgkin Lymphomaand Literature Review |
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| DOI： |
| 中文关键词: 骨髓增生异常综合征 非霍奇金淋巴瘤 |
| 英文关键词: Myelodysplastic syndrome Non-Hodgkin lymphoma |
| 基金项目:黑龙江省教育厅科学技术研究项目(12541530) |
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| 中文摘要: |
| 目的：探讨骨髓增生异常综合征合并非霍奇金淋巴瘤的发病机制、诊断及治疗，并判断其预后情况。方法：回顾我院收治的
一例骨髓增生异常综合征（MDS）患者同时诊断间变大细胞淋巴瘤（ALCL）患者的临床资料，总结其诊断及治疗经过，对其预后进
行评价。结果：该患者诊断间变大细胞淋巴瘤后，经化疗对症治疗病情无显著改善，且患者ALK 阳性，考虑预后较差，建议造血干
细胞移植。结论：骨髓增生异常综合征合并非霍奇金淋巴瘤的病例在国内外十分罕见，治疗方法目前尚需进一步研究。 |
| 英文摘要: |
| Objective:To investigate the pathogenesis, diagnosis and treatment of myelodysplastic syndromes with non-hodgkin
lymphoma and evaluate the prognosis.Methods:The clinical date of 1 case of patient with myelodysplastic syndromes (MDS) who was
diagnosed as anaplastic large cell lymphoma (ALCL) at the same time was retrospectively reviewed, the diagnosis and treatment procedure
were summarized and the prognosis was evaluated.Results:With the diagnosis of ALCL, the patient's condition had no significant
progression after symptomatic treatment of chemotherapy, as the ALK was positive, we considered the prognosis was poor, suggested
hematopoietic stem cell transplantation.Conclusion:The case of myelodysplastic syndromes with non-hodgkin lymphoma was very rare
at home and aboard, the method of treatment was still needed further research at present. |
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