| 张建华 李辉 赵慧英 田洪森 刘津军.慢性心力衰竭院内感染病原菌监测及危险因素分析[J].,2016,16(26):5149-5152 |
| 慢性心力衰竭院内感染病原菌监测及危险因素分析 |
| Surveillance of Nosocomial Infection Pathogens in Patients with ChronicHeart Failure and Its Risk Factors Analysis |
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| DOI： |
| 中文关键词: 慢性心力衰竭 医院感染 病原菌 危险因素 |
| 英文关键词: Chronic heart failure Nosocomial infection Pathogenic bacteria Risk factors |
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| 中文摘要: |
| 目的：探究慢性心力衰竭(CHF)患者医院感染的现状、病原菌分布及耐药情况，分析CHF患者发生医院内感染的危险因素。
方法：选择2012 年9 月~2015 年9 月中心医院及开发区分院收治的390 例CHF 患者为研究对象，根据CHF患者是否发生医院
内感染将其分为观察组（感染患者41 例）和对照组（未感染患者349 例）；收集患者基线资料，对观察组患者进行病原菌培养及药
敏实验，分析CHF患者发生医院内感染的危险因素。结果：CHF患者中医院感染的发生率为10.51%(41/390)，感染部位以呼吸道
19 例（46.34%）和泌尿道12（29.27%）为主；前三位的病原菌为铜绿假单胞菌14 株（29.79%）、大肠埃希菌11 株（23.40%）和肺炎克
雷伯菌8 株（17.02%）；铜绿假单胞菌、大肠埃希菌和肺炎克雷伯菌对头孢哌酮、美罗培南及亚胺培南均具有药物敏感性；年龄≥
60 岁（OR=2.26，P<0.05）、住院时间≥ 2 两个月(OR=5.12，P<0.05)、有侵袭性操作(OR=7.45，P<0.05)、病程长(OR=4.36，P<0.05)是
CHF患者发生医院内感染的危险因素。结论：CHF患者医院感染的发生率较高，年龄≥ 60 岁、住院时间≥ 2 个月、侵袭性操作及病
程>5 年是CHF 患者发生医院内感染的危险因素；应当针对患者医院感染特点及药敏实验结果，采取针对性的预防措施和对策，
有效控制及降低医院感染的发生。 |
| 英文摘要: |
| Objective:To explore the status, pathogenic bacteria distribution, drug resistance and risk factors of nosocomial
infection in chronic heart failure (CHF)patients.Methods:Selected 390 cases of patients with CHF treated in the central hospital and
development branch hospital from September 2012 to September 2015 as research object, which were divided into observation group (41
cases of patients with nosocomial infection) and control group (349 cases of patients without nosocomial infection)according to whether
or not occured the hospital infection in patients with CHF; Collected the base information of patients, Culture and drug sensitivity test of
pathogenic bacteria were given for the patients in observation group, and analyzed the risk factors of nosocomial infection in CHF
patients.Results:The incidence of nosocomial infection in CHF was 10.51%(41/390), and the main infection site were 12 cases of
respiratory tract (46.34%)and 19 cases of urinary tract (29.27%); The top three pathogens were 14 strains of
(29.79%), 11 strains of (23.40%)and 8 strains of (17.02%); Which had drug sensitivity in
cefoperazone, meropenem and imipenem; Age≥ 60 years (OR=2.26, P<0.05), hospitalization time≥ 2 months (OR=5.12, P<0.05), had
invasive manipulation(OR=7.45, P<0.05), course of disease＞5 years(OR=4.36, P<0.05) were the risk factors of nosocomial infection in
patients with CHF.Conclusion:The incidence of nosocomial infection in CHF is highly, age≥ 60 years, hospitalization time≥ 2 months,
have invasive manipulation, course of disease＞5 years are the risk factors of nosocomial infection in patients with CHF, according to the
characteristics of hospital infection and drug sensitivity test results, we should take preventive measures and measures to effectively
control and reduce the incidence of hospital infection. |
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