| 于洋 莫波△ 徐兵 闽春明 马娟 王丽.CT联合肿瘤标志物与MRI联合肿瘤标志物对于直肠癌患者术前诊断
的准确率与特异性的研究[J].,2016,16(25):4962-4965 |
| CT联合肿瘤标志物与MRI联合肿瘤标志物对于直肠癌患者术前诊断
的准确率与特异性的研究 |
| A Comparative Study on Diagnostic Value of CT with Tumor Markers andMRI with Tumor Markers in Accuracy and Specificity for Rectal Cancer |
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| DOI： |
| 中文关键词: CT 联合肿瘤标志物 MRI联合肿瘤标志物 直肠癌 准确率与特异性 |
| 英文关键词: CT with tumor markers MRI with tumor markers Colorectal cancer Accuracy and specificity |
| 基金项目:湖北医药学院附属人民医院2014 年院级科研计划项目（2014zd06） |
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| 中文摘要: |
| 目的：探讨CT 联合肿瘤标志物与MRI联合肿瘤标志物对于直肠癌患者术前诊断的准确率与特异性，为大肠癌的术前诊断
提供一定的理论依据。方法：选取我院在2015 年01 月至2016 年01 月间收治的86 例直肠癌患者以及64 例肠道良性病变患者
分别作为观察组I组和观察II组的研究对象，另外选取来我院进行健康体检的80 例人员作为对照组研究，分别分析CT 联合肿
瘤标志物与MRI联合肿瘤标志物（CEA、CA125、CA199、CA242、CA724）对大肠癌患者诊断的准确率与特异性之间的差别。结果：
观察I组肿瘤标志物水平要明显高于观察II 组和对照组，差异显著，具有统计学意义；肿瘤标志物CEA、CA125、CA199、CA242、
CA724 对大肠癌患者检测的阳性率分别为67.44 %（58/86）、26.74 %（23/86）、84.88 %（73/86）、72.09 %（62/86）、33.72 %（29/86），肿
瘤标志物并联检测对大肠癌的阳性检测率为94.19 %（81/86）。CT 联合肿瘤标志物对大肠癌的准确率为97.67 %(84/86)，特异性为
94.44 %（136/144）；MRI联合肿瘤标志物对大肠癌的阳性检测率为100.00 %（86/86），特异性为98.61 %（142/144）。结论：CT 联合
肿瘤标志物对大肠癌诊断的准确率与特异性均不如MRI联合肿瘤标志物，因此MRI联合肿瘤标志物可作为大肠癌除病理学鉴
定外最佳的诊断方式。 |
| 英文摘要: |
| Objective:To investigate the accurate rate and specificity of preoperative diagnosis for patients with rectal cancer by
CT combined with tumor markers and MRI combined with tumor markers,and provide a theoretical basis for the preoperative diagnosis
of colorectal cancer.Methods:Eighty six cases of colorectal cancer patients and 64 cases of benign intestinal lesions in our hospital between
January 2015 to January 2016 were observed for observation group I and group II, in addition to our hospital were selected 80 cases
of healthy people as a control group study.The accurate rate and specificity of preoperative diagnosis for patients with rectal cancer by CT
combined with tumor markers (CEA, CA125, CA199, CA242, CA724) and MRI combined with tumor markers were analyzed separately.Results:Tumor markers of observation group I was significantly higher than observed group II and the control group, the difference was
significant. Tumor markers CEA, CA125, CA199, CA242, CA724 positive rate of detection of colorectal cancer patients was 67.44 %
(58/86) respectively, 26.74 % (23/86), 84.88 % (73/86), 72.09 % (62/86), 33.72 % (29/86), parallel detection of tumor markers in colorectal
cancer detection rate was 94.19%positive (81/86). CT combined tumor markers for colorectal accuracy was 97.67 %(84/86) and
a specificity of 94.44% (136/144); MRI combined with tumor markers for colorectal cancer positive test was 100.00 % (86/86) and a
specificity of 98.61 %(142/144).Conclusion:The accuracy and specificity of CT combined with tumor markers in colorectal cancer diagnosis
are not as good as MRI combined with tumor markers, therefore, MRI combined with tumor markers can be used as the best way
to diagnose colorectal cancer. |
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