| 胡泳 方立明 张敏 韦玲 王硕朋.醋酸钙联合左卡尼汀对维持性血液透析患者钙磷代谢的影响[J].,2015,15(36):7085-7087 |
| 醋酸钙联合左卡尼汀对维持性血液透析患者钙磷代谢的影响 |
| Effect of CalciumAcetate Combined with Levocarnitine on CalciumandPhosphorus Metabolismin Maintenance Hemodialysis Patients |
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| DOI： |
| 中文关键词: 醋酸钙 左卡尼汀 维持性血液透析 甲状旁腺素 钙磷代谢 |
| 英文关键词: Calciumacetate L-carnitine Hemodialysis Parathyroid hormone Calciumand phosphorus metabolism |
| 基金项目:江苏省中医药科技资助项目(LZ13074) |
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| 中文摘要: |
| 目的：研究并评价醋酸钙联合左卡尼汀对维持性血液透析患者钙磷代谢的影响，为临床治疗提供参考依据。方法：以2013 年
8 月至2015 年2 月在我院进行维持性血液透析的50 例患者作为研究对象，按照随机法分为两组，其中对照组患者给予醋酸钙治
疗，研究组患者给予醋酸钙联合左卡尼汀治疗，比较两组患者治疗前后全段甲状旁腺素、血钙、血磷、钙磷乘积的变化。结果：与对
照组比较，研究组患者全段甲状旁腺素、血钙、血磷、钙磷乘积水平均在正常范围内，较对照组有明显改善(P<0.05)；研究组全段甲
状旁腺素、血钙、血磷、钙磷乘积达标率分别为68.00%、84.00%、64.00%、80.00%，与对照组比较，血磷达标率不具有统计学差异
(P＞0.05)；全段甲状旁腺素、血钙及钙磷乘积达标率差异具有统计学意义(P<0.05)。结论：醋酸钙联合左卡尼汀对维持性血液透析
患者甲状旁腺素、钙磷代谢的改善效果较单用醋酸钙更佳。 |
| 英文摘要: |
| Objective:To research and evaluate the effect of L-carnitine combined with calcium acetate on calcium and
phosphorus metabolism in maintenance hemodialysis patients, thereby provide references for clinical treatment.Methods:50 cases of
patients with maintenance hemodialysis admitted from August 2013 to February 2015 in our hospital were selected and randomly divided
into two groups, The control group was treated with calcium acetate, while the study group was treated with L-carnitine combined with
calcium acetate; Then the changes of parathyroid hormone, calcium and phosphorus metabolism, calcium-phosphorus product in both
groups before and after treatment were compared.Results:Compared with the control group, the intact parathyroid hormone, calcium,
phosphorus and calcium-phosphoru of study group were within the normal range, a significant improvement compared with the control
group and before treatment (P<0.05). The compliance rates of intact parathyroid hormone, calcium, phosphorus and calcium-phosphorus
of study group were 68.00%, 84.00%, 64.00%, 80.00%. Compared with the control group, no statistical difference was found in the
phosphorus compliance rates (P＞0.05), but intact parathyroid hormone and calcium and phosphorus product compliance rates were
significantly different (P<0.05).Conclusion:Calcium acetate combined with L-carnitine had better effect on maintenance hemodialysis
patients, which improved the effcacy of parathyroid hormone, calciumand phosphorus metabolism. |
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