| 倪高顺 谢永红 吴凤琴 陈洋 朱先鹏.重症肺炎患者PCT, WBC, CRP 水平与预后的相关性分析[J].,2015,15(32):6334-6337 |
| 重症肺炎患者PCT, WBC, CRP 水平与预后的相关性分析 |
| Correlation Analysis of PCT,WBC, CRPand Prognosis of Severe Pneumonia |
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| DOI： |
| 中文关键词: 降钙素原 重症肺炎 WBC C-反应蛋白 |
| 英文关键词: Procalcitonin Severe pneumonia WBC C- reactive protein |
| 基金项目:国家自然科学基金项目(81372288) |
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| 中文摘要: |
| 目的：探讨重症肺炎患者降钙素原（PCT）、白细胞（WBC）、C- 反应蛋白（CRP）水平与疾病的相关性。方法：回顾性分析我院
ICU 收治的101 例重症肺炎患者，患者均采取机械通气治疗，根据生存情况分为分为生存组与死亡组，另选取同期体检的正常人
共40 例作为对照组。在住院时、入院后第1 d、5 d以及转出ICU(或死亡时)抽取外周血检测血清PCT、WBC 以及CRP水平，同时
进行APACHEⅡ评分，并应用统计学分析方法进行数据的相关性分析。结果：①与正常人群相比，重症肺炎患者的PCT、WBC以
及CRP 显著升高，与死亡组同期比较，生存组PCT、WBC以及CRP较低，P＜0.05；②与死亡组同期比较，生存组APACHEⅡ评分
较低，P＜0.05；③相关性分析结果显示WBC、CRP、PCT 与APACHEⅡ评分呈正相关P＜0.01。结论：重症肺炎患者的血清PCT、
WBC以及CRP水平升高明显，有利于判断重症肺炎病情，对评估预后具有一定的价值。 |
| 英文摘要: |
| Objective:To investigate the correlation of PCT, WBC, CRP and prognosis of severe pneumonia.Methods:A
retrospective analysis of 101 cases of severe pneumonia patients in our hospital were treated by mechanical ventilation. According to the
survival circumstances were divided into survival group and death group. Another 40 cases of normal physical examination were selected
as the control group. The level of PCT, WBC and CRP of peripheral blood serum and APACHE score at the time of admission, 1 d, 5 d
after admission and the time transformed fromICU or the time of death.Results:The level of PCT, WBC and CRP of patients with severe
pneumonia was increased significantly, and PCT, WBC and CRP in the survival group was lower compared with the death group, P<0.
05, Compared with the death group, APACHE score in the survival group was low, P<0.05. The correlation analysis showed that WBC,
CRP, PCT was positively correlated with APACHE II score.Conclusion:The serum level of PCT, WBC and CRP was increased
significantly in the patients with severe pneumonia, so it has a certain value to assess the prognosis of the severe pneumonia through the
detection of serumPCT, WBC and CRP. |
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