| 安凌王 陈林慧 申红 朱兰萍 樊树清 杨玉兰 汤虹 徐慧君 李洮俊
司春燕 赵薇 滕雪玲 韩立华 孙双庆 刘春艳 李建平 张陆萍 原海琴
刘瑜 吴丽 饶君 张芳琴 陈文蕊 庞雅婷 李文娟 李锐娟 张雪珠
王红 杨巍 胡肇衡 纪立农.第一滴和第二滴末梢血血糖值差异性的多中心临床研究[J].,2015,15(31):6086-6090 |
| 第一滴和第二滴末梢血血糖值差异性的多中心临床研究 |
| Difference between Blood Glucose Values of First and Second Drop ofPeripheral Blood |
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| DOI： |
| 中文关键词: 血糖监测 糖尿病 自我管理 第一滴血 多中心临床研究 |
| 英文关键词: Blood glucose monitoring Diabetes Self-management The first drop Multicenter clinical trial |
| 基金项目: |
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| 中文摘要: |
| 目的：本研究旨在探讨在洗手消毒和不洗手消毒两种情况下，第一滴与第二滴末梢血血糖值之间的差异，以及第一滴末梢
血血糖值与对照血糖值之间的差异，及此差异对临床治疗决策的影响。方法：研究于2014 年5 月20 日至5 月29 日在全国四
个城市的四家糖尿病专科医院中同步进行，共纳入住院糖尿病患者240 例，分别测定洗手消毒以及不洗手不消毒情况下第一滴
和第二滴末梢血的血糖值，使用Wilcoxon 符号秩和检验方法比较第一滴与第二滴末梢血血糖值及第一滴末梢血与对照血糖值，
利用误差栅格分析（Error Grid Analyze, EGA）图分析第一滴与第二滴末梢血血糖值及第一滴末梢血与对照血糖值的一致性。
结果：分别获得洗手消毒和不洗手消毒情况下的血糖监测结果1183 对和715 对。无论是否洗手消毒，第一滴与第二滴末梢血的
血糖值以及第一滴末梢血与对照血糖值之间的差异均具有统计学意义（P 值均为0.000）。在洗手消毒和不洗手消毒情况下，第一
滴与第二滴末梢血血糖值偏差小于20 %的百分比分别为98.6 %和97.8 %，落于EGA 图的A 区；第一滴末梢血与对照组血糖值
的偏差小于10%的百分比分别为98.2 %和97.6 %，在EGA 图中，落于A区的百分比分别为99.8 %和99.6 %。结论：在糖尿病
的自我管理和临床实践中，无论是否洗手消毒，使用第一滴末梢血进行血糖监测已经足够准确可靠，且更为方便快捷。 |
| 英文摘要: |
| Objective:The blood glucose monitoring is an important part of diabetes care. However, whether the first drop of
blood or the second for glucose monitoring is not clearly put forward in the domestic and international guidelines. The purpose of this
study is to investigate the difference between the first drop of peripheral blood and the second in the two cases of hand washing and disinfection
and no hand washing and disinfection.Methods:The study was conducted in four diabetes special hospitals in four cities in China
from May 20, 2014 to May 29th; 240 patients with diabetes were admitted to the four diabetes special hospitals. Blood glucose values of
the first and second drops of blood were measured in the two cases of hand washing and disinfection and no hand washing and disinfection.
The difference between the first and second drops of capillary glucose concentrations and the difference between the first drop and
the control measurement were compared by using the Wilcoxon signed rank test method and the Error Grid Analyze (EGA) graph.Results:A total of 1183 and 715 pairs of blood glucose monitoring results were obtained in the two cases of hand washing and disinfection and no hand washing and disinfection. Whether with or without hand washing and disinfection, there were statistically significant differences in
blood glucose values between the first and second drops of blood and between the first drop of blood and control blood glucose (P =
0.000). In the two cases of hand washing and disinfection and no hand washing and disinfection, percent of deviation less than 20% in
blood glucose values of the first drop and second drops of blood were 98.6 % and 97.8 %, which were in Zone A of the EGA map; percent
of deviation less than 10%in blood glucose values of the first drop and control measurment were 98.2 %and 97.6 %, the percent in
Zone A of the EGA map were 99.8 % and 99.6 %.Conclusion:On account of the sufficient accuracy, reliability and convenience, the
first drop of blood can be used for self-monitored glucose testing and clinical practice, whether or not hand washing disinfection. |
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