| Kidney Yang deficiency syndrome is caused by kidney Yang deficiency and mal-nutrition, which is a kind of
deficiency-cold syndrome. It is widely observed in asthma, diarrhea, edema, uroschesis, erectile dysfunction, leucorrhea, consumptive
disease, chronic nephritis, chronic renal failure, chronic enteritis, hypocorticalism and chronic heart failure. As one of the important
syndrome in TCM theoretical system, the researches have lasted for several decades. In the researches of its animal model, mechanism,
gene expression, metabonomics, the functions of hypothalamus-pituitary-targeted axis, renal, immune system, Specific Proteins were
widely used as the evaluation index as well as the energy metabolism, cyclic nucleotide system, free radical metabolism and cell signal
transduction system. However, there are no generally accepted standardized biochemical indicators of kidney-yang deficiency. This paper
summarized the recent advances in the biochemical indicators of kidney-yang deficiency, and provides a new clue to the further research
into kidney-yang deficiency. The author thinks metabolomics as a scientific, quantitative analysis methods, which use the advanced
analytical techniques and pattern recognition methods. It can effectively avoid illness subjective factors of uncertainty as a research
method. |
