| 王慧娟 秦俭 万云高 曹涛 王长远.初发急性ST 段抬高心肌梗死患者预后的影响因素分析[J].,2015,15(29):5651-5654 |
| 初发急性ST 段抬高心肌梗死患者预后的影响因素分析 |
| Aanalysis of Prognosis Influence Factors in Patients with Initial OnsetST-segment Elevation Myocardial Infarction |
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| DOI： |
| 中文关键词: 急性心肌梗死 PCI 血糖 高敏C反应蛋白 预后 |
| 英文关键词: Acute myocaidial infarction PCI Blood glucose High sensitivity c-reactive protein(HsCRP) Prognosis |
| 基金项目:卫生部卫生行业基金科研专项项目（201002011） |
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| 中文摘要: |
| 目的：研究初发急性ST 段抬高心肌梗死患者预后的影响因素。方法：选取我院2010 年收治的发病24 小时内初发急性ST
段抬高心肌梗死（ST-segment elevation myocardial infarction, STEMI）258 例，收集患者病史、化验检查、心脏彩超、冠状动脉造影结
果等住院资料，并随访主要心血管事件，通过相关分析求出对预后有统计学意义的因素，再分别通过Logistic 回归及Cox 回归分
析急性心肌梗死患者近期及远期预后的影响因素。结果：AMI 患者住院死亡率6.2%（16/258 例），影响住院死亡率因素为PCI治
疗(r=-0.253, P=0.000, OR=0.318, 95%CI: 0.101-0.997) 、血糖（Glu）(r=0.24, P=0.01, OR=1.136, 95%CI: 1.020-1.265)两个因素；平均
随访7.6± 3.8 月，总终点事件10.3%（25/242 例）,心源性死亡患者6 例（2.5%）；经Cox 回归分析与远期死亡相关的因素是高敏C
反应蛋白（HsCRP）（r=0.182，P=0.008，OR=1.223，95%CI：1.065-1.403）。结论：急性心肌梗死预后受多种因素影响，影响住院死亡率
的因素为PCI治疗及血糖，影响远期死亡的因素是HsCRP。 |
| 英文摘要: |
| Objective:To Study the influence factors for prognosis of initial onset ST elevated myocardial infarction patients.Methods:We selected 258 cases of ST-segment elevation myocardial infarction(STEMI) patients in our hospital in 2010 as research subjects,
whose symptoms were onset in 24 hour, colleted patients informations of medical histories, laboratory examinations, UCG and
CAG, and followed up major cardiovascular events. To analyse the statistically significant influence factors for prognosis by correlation
analysis, then through Logistic regression and Cox regression analyse the influence factors for short and long-term prognosis of AMI patients.Results:The resident death rate of AMI patients was 6.2%（16/258）, and the influence factors with resident death of AMI hospitalized
patients were primary PCI (r=-0.253, P=0.000, OR=0.318, 95%CI: 0.101-0.997) and fasting blood glucose levels (r=0.24, P=0.01,
OR=1.136, 95%CI: 1.020-1.265); Followed up on average 7.6± 3.8 months, the total major cardiovascular events were 10.3%(25/242),
the percentage of cardiac death was 2.5%(6/242); The influence factor with long-term death rate of AMI patients through Cox regression
was HsCRP concentration (r=0.182, P=0.008, OR=1.223, 95%CI：1.065-1.403).Conclusion:There were several reasons for short and
long-termprognosis of AMI patients. The influence factors with resident death of AMI hospitalized patients were primary PCI and fasting
blood glucose levels, and the influence factor with long-termdeath rate of AMI patients was HsCRP. |
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