Myocardial remodeling is known as at the effect of some physiological or pathological stimulation on the heart,
cardiomyocytes and cardiac extracellular matrix occurred significant changes in the cell structure, function, quantity and heritable
phenotype, as well as changes in heart size, shape and function. Myocardial cells and myocardial extracellular matrix fundamentally
involved in the process of cardiac remodeling. Currently, the factors that affect cardiac remodeling and related mechanism focused on
aspects of hemodynamic and neurohormonal. In recent years, a reversal of interventions on the adverse cardiac remodeling, including
intervention, exercise intervention, has been ongoing,with deepening of the research, the improvement of related diseases and treatment
appeared new progress and hope. Myocardial remodeling may be physiological or pathological, physiological remodeling is adaptive
compensatory changes in myocardial, pathological remodeling is not suited for the body and produce harmful to our health. The main
part of the paper focuses on pathological cardiac remodeling, influencing factors and related mechanisms of cardiac remodeling,
improvement of adverse cardiac remodeling, and make prospects. |