| 周叶 彭利 李建华 晏沐阳.BMI 及 LDL-C 水平与冠脉慢血流的相关性研究[J].,2015,15(7):1201-1204 |
| BMI 及 LDL-C 水平与冠脉慢血流的相关性研究 |
| Correlation between LDL-C, BMI and Coronary Slow Flow |
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| DOI： |
| 中文关键词: 冠状动脉慢血流现象 低密度脂蛋白 胆固醇 身体质量指数 危险因 素 |
| 英文关键词: Coronary slow flow phenomenon Low-density lipoprotein Body mass index Risk factor |
| 基金项目:国家自 然科学基金项目（ 81073093） |
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| 中文摘要: |
| 目的： 探讨低密度脂蛋白 胆固 醇及身高体重指数与 冠状动脉慢血流现象（ Coronary slow flow phenomenon,CSFP）的相关性。
方法： 在我院 2013 年上半年因 不典型胸痛行冠脉造影术患者中， 选取冠脉官腔无明显狭窄（ <40 %）且至少一支冠脉根据校正的
TIMI 血流分级方法被评为 慢血流的患者进入慢血流组（ CSFP 组）79 例 ， 选取同期无明显狭窄且血流速度正常的患者 71 例为 对
照组， 对两组入院各项常规检查检验指标进行分析， 筛 选导致冠脉慢血流的危险因 素。 结果： 在两组比较中， CSFP 组的慢血流组
吸烟率、身体质量指数（ Body Mass Index, BMI）、甘油三酯（ Triglyceride, TG）、低密度脂蛋白胆固醇（ Low density lipoprotein cholesterol, LDL-C）、尿酸（ Uric acid, UA）水平明显高于对照组；亚组分析中显示 BMI、LDL-C 水平随受累 血管数量增多呈上升趋势，且
具有统计学意义； 经回归分析，显示 BMI、LDL-C 水平的升高对冠脉慢血流的发生有显著影响， 且与冠脉血流速度（帧数）呈正相
关。 结论： BMI、 LDL-C 水平与冠脉慢血流的发病的密切相关。 |
| 英文摘要: |
| Objective:The aim of this research is to study the correlations between LDL-C, BMI and coronary slow flow phenomenon (CSFP).Methods:The 1 50 patients with chest pain, who were underwent coronary angiography, were divided by corrected TIMI
frame count(CSFP was defined as frame count >27) into CSF group(79) and control group(71). Body mass index (BMI), age, gender, history of smoking, hypertension, diabetes and hyperlipidemia were recorded and the total cholesterol (TC), triglyceride (TG), Low-density
lipoprotein (LDL-C), high-density lipoprotein (HDL-C), uric acid (UA), creatinine (Cr), left ventricular ejection fraction (EF), Systolic
blood pressure(SBP) and Diastolic blood pressure(DBP) were measured on admission.Results:The smoking rate, BMI, TG, LDL-C, UA
was significantly higher in the patients with the CSF group than the control group. BMI, LDL-C in the CSF group increased significantly
with increasing vessel involvement. The logistic regression analysis showed that BMI and LDL-C were the influence factor for coronary
slow flow, and were positively correlated with CSFP.Conclusion:CSFP is associated with BMI and LDL-C. |
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