| 贺 星 崔立红△ 王晓辉 闫志辉 李 超.结肠息肉镜下特征、病理分型及癌变规律分析[J].,2014,14(35):6893-68896 |
| 结肠息肉镜下特征、病理分型及癌变规律分析 |
| Analysis of Enteroscopic Characteristics, Pathological Type and CancerousRules of Colorectal Polyps* |
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| DOI： |
| 中文关键词: 结肠息肉 结肠镜 病理学 癌变 癌胚抗原 |
| 英文关键词: Colorectal polyps Colonoscopy Pathology Cancerization Carcinoembryonic antigen |
| 基金项目:北京市科委科研基金项目（ Z11 1107067311 051） |
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| 中文摘要: |
| 目的： 探讨结肠息肉 镜下特征、病理类型及血清学特点与 癌变的相关性。 方法： 收集我院 2011 年 6 月 ～ 2013 年 6 月 肠镜证
实的 640 名结肠息肉 患者资料。 对年龄、性别、息肉 特征（部位、大小、数量、分型、病理等）分析,并将息肉 者癌胚抗原与 健康人比
较。 结果： 检出 息肉 11 44 枚； 年龄在 41 岁 ～ 60 岁的占 52.9%； 发生在乙状结肠和直肠的占 47.3％ ； 多 发及多 部位息肉 比例为
56.9%和 46.9%； 腺瘤样息肉占 87%； 随年龄、息肉 体积增加,癌变率增加； 无蒂息肉 癌变率高于有蒂息肉 ； 两组血清癌胚抗原值差
异有统计学意义。 结论： 结肠息肉 多 发生在乙状结肠和直肠； 以腺瘤息肉 为主；癌变与 年龄、腺瘤大小、形态、病理类型有关。癌胚
抗原可能在腺瘤样息肉 的筛查及监测癌变存在意义。 |
| 英文摘要: |
| Objective:To study the enteroscopic characteristics, pathological type as well as serological characteristics of colorectal polyps and to analyze their association with Cancerization.Methods:The datas of 640 patients with colorectal polyps were collected,
all the patients were diagnosed by colonoscopy and pathological evidence in our hospital from June 201 1 to June 2013. The age, sex, and
the characteristics of the polyp (1ocation, size, number, classification and pathological type etc) were analyzed. The carcinoembryonic
antigen detection were retrospectively studied in 640 patients with colorectal polyp and 200 healthy people as the control group, the data
were statistically analyzed.Results:11 44 polyps were founnd in 640 patients by colonoscopy. The age of 52.9% of the patients was
ranged from 41 to 60 years 47.3% of polyps were located in sigmoid colon and rectum. The rate of multiple polyps and multiple sites simultaneously violation polyps were 56.9% and 46.9%. In all the 11 44 polys, adenomatous polyps were 996 (87%). The larger the diameters the higher the chance for Cancerization of the polyps; the older age, the higher the chance for Cancerization of the polyps. The
chance for Cancerization in sessile polyps is higher than pedunculated polyps. There were significant difference of the Carcinoembryonic
antigen values between patients with colorectal polyp and Healthy people.Conclusion:Colorectal polypus occurred more often in middle
aged people (41 -60 years). The lesions revealed by colonoscopy were mainly located in rectum and sigmoid colon. The Proportion of
multiple polyps and multiple sites simultaneously violation polyps increase. The major pathological type is adenoma. The likelihood of
Cancerization of colorectal polyps seemed to be correlated with the age, size, appearance and pathological type. Carcinoembryonic antigen may be valuable in screening the adenomatous polyps and to monitoring the early colorectal cancerization. |
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