| 张来 赵卫红 周瑛 邱君思 阎丰 黄海华 宋丹.PTH
、 BUN 及 CRe 联合检测对早期肾功能衰竭的诊断价值[J].,2014,14(35):6883-6885 |
| PTH
、 BUN 及 CRe 联合检测对早期肾功能衰竭的诊断价值 |
| Clinical Significance of Joint Detection of Parathyroid Hormone UreaNitrogen, Creatinine in the Diagnosis of Early Renal Failure |
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| DOI： |
| 中文关键词: 早期诊断 肾功能衰竭 尿素氮 甲状旁腺激素 肌酐 |
| 英文关键词: Early diagnosis Renal failure Urea nitrogen Parathyroid hormone Creatinine |
| 基金项目:2013 年度南京医科大学科技发展项目（ 201 3NJMU186）；国家自然科学基金项目 (81070588) |
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| 中文摘要: |
| 目 的： 探讨甲状旁腺激素、尿素氮及肌酐联合检测在肾功能衰竭患者早期诊断中的临床意义。 方法： 选取 2012 年 1 月 -2013
年 8 月 在我院接受治疗的 80 例 肾功能衰竭患者作为 研究对象， 另 选同 期体检正常人 40 例 为 对照组， 选用 我院全自 动化学分析
仪器及电化学发光免疫分析测量仪器检测患者血清中甲状胖腺激素、尿素氮及肌酐水平。 结果： 与 对照组患者比较， 观察组患者
血清样本中甲状旁腺激素水平、尿素氮水平与 肌酐水平呈显著增高趋势， 有统计学意义（ P＜ 0.05）。 肾功能衰竭患者在其代偿期血
清内三项水平呈显著增高趋势， 而在氮质血症期间 ， 血清内三项要素水平升高现象更为 显著， 而在尿毒症期间 ， 对比氮质血症期
间 同 样有其上升的表现， 突出表现为显著的增高态势。 结论： 在临床诊断中， 可将血清样本中甲状旁腺激素水平作为 判定其肾功
能衰竭严重程度的关键指标。 |
| 英文摘要: |
| Objective:To study the clinical significance and correlation of joint detection of parathyroid hormone, urea nitrogen
and creatinine in the diagnosis of early renal failure patients.Methods:80 patients with renal failure from January 201 2 to August 2013 in
our hospital were selected as the research object. Using the automatic chemical analysis instrument and the electrochemical luminescence
immunoassay measuring instrument, the level of parathyroid hormone in serum, urea nitrogen and creatinine was detected.Results:Compared with the control group patients, the levels of parathyroid hormone, urea nitrogen and creatinine in serum samples significantly
increased in observation group with obvious statistical significance(P<0.05). In the compensatory phase of renal failure, the three levels in
serum significantly increased, and during the period of azotemia, the elevated levels were more pronounced, and during the period of
uremia, the level of parathyroid hormone, urea nitrogen and creatinine also had a significant rise in comparison to the period of azotemia.Conclusion:In clinical diagnosis, the serum level of parathyroid hormone can be a key indicator of the severity of renal failure. |
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