| 刘小红 陆建平 汪剑 苗华栋 高勇 吴萱泽 陈健 郭丽玲 杨丽秀 蔡捷 施从忠 朱思光 刘畅.3.0T MR 波谱成像与扩散结合在前列腺中央腺体癌诊断中的价值[J].,2014,14(33):6523-6526 |
| 3.0T MR 波谱成像与扩散结合在前列腺中央腺体癌诊断中的价值 |
| Value of 3.0T MR Spectroscopy Combined with Diffusion Weighted Imagingin Prostatic Central Gland Cancer Diagnosis |
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| DOI： |
| 中文关键词: 前列腺癌 磁共振成像 扩散加权成像 磁共振波谱分析 |
| 英文关键词: Prostate cancer MR imaging Diffusion -weighted imaging MR spectroscopy |
| 基金项目:上海虹口区科委医学科研课题（1102－20）；上海市卫生局基金项目（2010040） |
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| 中文摘要: |
| 要目的：探讨3.0T 磁共振波谱成像(MRSI) 结合扩散加权成像(DWI) 在前列腺中央腺体癌中的诊断价值。方法：回顾性分析术
前MRSI 与DWI结合诊断为前列腺中央腺体癌的患者共18 例，术后确诊为前列腺癌16 例、前列增生1 例、前列腺增生伴前列腺
中度到重度炎症1 例。其中3 例已经确诊中央腺体癌为激素治疗后行MRI检查。比较患者癌区与对侧非癌区两组间的(胆碱+肌
酸)/枸橼酸盐(CC/C)值。结果：无任何治疗的13 例中央腺体癌区158 个体素的CC/C 值均值为2.684± 1.7，非癌区196 个体素的
CC/C 均值为0.49± 0.08。（T 值为2.778，P 值均=0.017＜0.05 )，中央腺体癌区与对侧非癌区之间的CC/C 值差异有统计学意义。3
例激素去势治疗后癌区的CC/C 均值为1.18± 0.95，非癌区22个体素CC/C均值为0.46± 0.255。（T 值为1.196，P值均=0.354>0.05)
。激素治疗后中央腺体癌区与对侧非癌区之间的CC/C 值差异无统计学意义。结论：MRSI结合DWI显著提高前列腺中央腺体癌
的诊断。 |
| 英文摘要: |
| Objective:To discuss the value of 3.0T MR spectroscopic imaging (MRSI) combined with diffusion-weighted
imaging (DWI) in detecting the prostatic central gland cancer.Methods:The clinical and MR imaging data of 18 patients were analyzed
retrospectively, here were 16 cases suffered from prostatic central gland cancer after surgery, 1 case suffered from prostate hyperplasia,
and 1 case suffered from prostate hyperplasia and inflammation from mid to high level. 3 cases among the 16 cancer had been treated
with hormone before MRI. CC/C values of patients’cancerous zone and non-cancerous zone were compared.Results:In the prostatic
central gland cancer zone, the 158 voxels’CC/C average value of the 13 cases without any treatment is 2.684± 1.7, however, the CC/C
average of 196 voxels is only 0.49± 0. 08 in the non-cancerous zone, which has statistically significant difference between the CC/C
value of the prostatic central gland cancer and non-cancer zone without any treatment (T values were 2.778, P values =0.017 < 0.05). As
for the 3 cases, which took the hormone therapy, heir 44 voxels' CC/C average value of cancerous zone is 1.18 ± 0. 95, and the 22
voxels’CC/C average value of non-cancerous zone is 0.46± 0. 255, which has no statistically significant difference between the CC/C
value of the prostatic central gland cancer and non-cancer zone after treated of hormone (T values were1.196, P values=0.354 < 0.05 ).Conclusion:MRSI combined with DWI significantly improve the central gland prostate cancer diagnosis. |
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