| 任丽楠 郭晓钟 李宏宇 姚辉 吴春燕 邹德莉.鼠药中毒引起消化道出血25例临床诊治分析[J].,2014,14(23):4513-4515 |
| 鼠药中毒引起消化道出血25例临床诊治分析 |
| Analysis of 25 Gastrointestinal Hemorrhage Patients Induced by Rodenticide Poisoning |
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| DOI： |
| 中文关键词: 鼠药中毒 消化道出血 凝血机制 |
| 英文关键词: Rodenticide poisoning Gastrointestinal hemorrhage Mechanismof coagulation |
| 基金项目:国家自然科学基金项目（81071982）；辽宁省博士科研启动基金项目（20111094） |
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| 中文摘要: |
| 目的：城市中杀鼠药中毒容易被临床医师忽视，其引起消化道出血也极易误诊和漏诊，本文分析抗凝血杀鼠药中毒至消化
道出血患者的临床表现和诊治方法。方法：回顾性分析2010 年1月至2013 年8 月间我院收治的25例杀鼠药中毒并出现消化道
出血病例，对其临床表现和诊治方法进行分析总结，病例均以维生素K1 抗凝血方法进行治疗，并比较分析治疗前后患者的凝血
酶原时间（PT）、国际正常化比率（INR）、活化部分凝血活酶时间（APTT）、纤维蛋白原（FIB）和出血时间（TT）等出凝血指标进行检
测，并进行比较分析。结果：25 例因抗凝血杀鼠药物中毒并导致消化道出血患者经维生素K1 等抗凝血方法治疗患者全部治愈，
消化道出血停止，凝血指标恢复正常，治疗前后患者的凝血指标存在明显差异（P＜ 0.05）。结论：抗凝血法对杀鼠药中毒导致消化
道出血进行治疗的临床效果显著，值得推广。 |
| 英文摘要: |
| Objective:Morbidity of rodenticide poisoning is lower in city. Gastrointestinal bleeding induced by rodenticide
poisoning is easy to be ignored or misdiagnosed. This study is to analyze gastrointestinal hemorrhage of patients induced by rat-poison
poisoning.Methods:The clinical data of 25 gastrointestinal hemorrhage patients induced by rat-poison poisoning during January 2010
and August 2013 in our hospital was retrospectively analyzed. The PT, APTT, TT, INR and FIB of the patients were detected and
compared before and after treatment with vitamin K1.Results:The 25 patients were recovered. There was obvious difference between
before and after treatment with vitamin K1 in the blood clotting index.Conclusion:The anti blood clotting is an available treatment to
rat-poison poisoning induced gastrointestinal hemorrhage. |
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