| 吴长东 张静 梁玥 刘政疆 薛克栋.AECOPD患者血清降钙素原与其它炎症指标水平的相关性分析[J].,2014,14(19):3726-3728 |
| AECOPD患者血清降钙素原与其它炎症指标水平的相关性分析 |
| Analysis of the Correlations of SerumProcalcitonin Level with OtherInflammatory Markers in Patients with AECOPD |
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| DOI： |
| 中文关键词: 慢性阻塞性肺疾病 降钙素原 超敏C 反应蛋白 白介素-6 |
| 英文关键词: Chronic obstructive pulmonary disease Procalcitonin High-sensitivity C-reactive protein Interleukin-6 |
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| 中文摘要: |
| 目的：分析慢性阻塞性肺疾病急性加重(AECOPD)患者血清降钙素原与其它炎症指标水平的相关性。方法：选择2012 年1
月至2012 年12 月我院重症医学科收治的195 例AECOPD 患者作为研究对象，所有患者均采血后行降钙素原(procalcitonin,
PCT)、超敏C 反应蛋白(C-reactive protein, hs-CRP)、血常规(blood General, WBC)、血沉(erythrocyte sedimentation rate, ESR)、白介
素六(interleukin-6, IL-6)检测，同时采集痰标本后行痰培养和药敏试验检测，分析其血清PCT 水平与其它炎症指标的相关性。结
果：195 例AECOPD 患者中，PCT 增高者43 例(22.1%)，正常者152 例(77.9%)，其血清PCT 水平与hs-CRP、WBC、中性粒细胞百
分比(neutrophil percentage, NEUT%)均显著相关(P<0.05)，相关系数分别为0.262、0.382、0.333，与ESR、IL-6、痰培养结果无明显相
关性(P>0.05)。结论：血清PCT 水平判定AECOPD患者是否合并感染有一定的局限性，联合检测hs-CRP、WBC、NEUT%，可作为
诊断AECOPD 感染的有力补充。 |
| 英文摘要: |
| Objective:To analyze the correlations of serum procalcitonin level with other inflammatory markers in patients with
AECOPD.Methods:195 patients with AECOPD hospitalized from January 2012 to December 2012 in critical care medicine of our
hospital were selected as research subjects, the serum procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), blood General,
erythrocyte sedimentation rate (ESR), interleukin-6 (IL-6) levels were detected, and the sputumsamples were underwent sputum culture
and sensitivity assay, the correlations between procalcitonin and other inflammatory markers were analyzed.Results:In 195 cases of
AECOPD, PCT levels were increased in 43 cases (22.1%) and normal in 152 cases (77.9%); PCT increased with The hs-CRP, WBC,
neutrophil percentage (NEUT%) were significantly different between AECOPD patients with normal and heighten serum PCT levels
(P<0.05). Positive correlations were found between serum PCT levels and hs-CRP, WBC, NEUT%of AECOPD patients(r=0.262, 0.382,
0.333, P<0.05).Conclusion:There were certain limitations of PCT in the determination of infection in patients with AECOPD, so
combined detection of hs-CRP, WBC, NEUT%could be used as complement. |
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