文章摘要
卫肖肖 1 尹彩星 1 马玉英 2△.血液透析对急性百草枯中毒的临床疗效分析[J].,2014,14(6):1109-1112
血液透析对急性百草枯中毒的临床疗效分析
Analysis of the Therapeutic Effect of Hemodilalysis in the Treatment ofParaquat Poisoning
  
DOI:
中文关键词: 血液透析  百草枯  中毒  临床疗效
英文关键词: Hemodialysis  Paraquat  Poisoning  Therapeutic effect
基金项目:
作者单位
卫肖肖 1 尹彩星 1 马玉英 2△ 1 石河子大学医学院 新疆 石河子 832000 2 石河子大学第一附属医院急诊内科 新疆 石河子 832000 
摘要点击次数: 818
全文下载次数: 1022
中文摘要:
      摘要 目的: 探讨血液透析 (hemodilalysis,HD ) 治疗急性百草枯中毒的临床疗效,为临床应用 HD 治疗急性百草枯中毒提供依据。 方法: 选择我院 2003 年 3 月 ~2012 年 7 月收治的百草枯中毒患者 40 例, 根据患者使用是否行透析治疗分为透析组(A 组 17 例) 和非透析组(B 组 23 例), 比较分析两组患者治疗后的肝功能、 肾功能、 肺功能及心肌酶学指标的变化, 治疗效果及存活情况。结 果: 两组患者入院后前 3 天 ALT、 AST、 BUN、 CR、 CK、 CK-MB 水平均呈上升趋势, 且非透析组患者以上指标的水平高于透析组患 者, 但差异无统计学意义(P>0.05), 入院后第 7 天, 两组以上指标的比较亦无统计学差异(P>0.05); 两组患者之间入院时和入院后 72 小时内最低的 SPO 2 %、 血气分析中 PaO2 和 PaCO2 水平比较无统计学意义(P>0.05); 透析组和非透析组患者的病死率分别为 70.6%和 69.6%, 差异无统计学意义(P>0.05)。结论: 百草枯溶液中毒的患者预后差、 病死率高, 血液透析治疗并不能显著提高急性 百草枯中毒患者的生存率。
英文摘要:
      ABSTRACT Objective:To investigate the clinical effects of hemodialysis (HD) on the treatment of paraquat poisoning.Methods: 40 patients with paraquat poisoning, who were admitted in our hospital from to March 2003 to July 2012 were divided into hemodialysis group (Group A) and non-hemodialysis group (Group B). We had comparative analysis analysis of the two groups of patients' objective indicators with liver function, kidney function, and cardiac enzymes, observe patient outcomes and survival rate.Results: The posttreatment Indexes such as ALT, AST, BUN, CR, CK-MB in groupB are higher than group A in the first three days, the level was still rising for two groups, and no significant different(P> 0.05 for all) was seen.The 7th day is also so(P> 0.05 for all). There is no statistical difference between two groups with the SPO 2 %, PaO2 , PaCO 2 at the 1st and the minimum value during 72 hours in hospital. The death rate in group A is 70.6% and group B is 69.6%, with no significance (P> 0.05).Conclusion: For the patients with poor prognosis and high mortality who oral 20% paraquat solution, hemodialysis treatment of pataquat poisoning patients can not appear to obviously improve the survival rate.
查看全文   查看/发表评论  下载PDF阅读器
关闭