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摘要目的：探讨行腹腔镜袖状胃切除术治疗合并2 型糖尿病（type 2 diabetes mellitus，T2DM）肥胖症病人的效果。方法：回顾性分析上海长征医院普外三科2008 年7月至2011 年12 月行腹腔镜袖状胃切除术治疗合并T2DM的肥胖症8 例病人的术前资料和术后12 个月的随访资料。结果：所有病人均在腹腔镜下完成手术，无中转开腹。术中术后均无严重并发症发生。在术后12 个月的随访过程中，病人体重、体重指数均呈下降趋势，与术前相比，术后1 月开始差异即有统计学意义（P＜0.01）。术后12 个月 T2DM临床完全缓解4 例（50%），临床部分缓解4 例（50%）。所有病人术后糖化血红蛋白、空腹血糖均呈下降趋势，从术后1 个月开始，糖化血红蛋白与术前相比差异有统计学意义（P＜0.01），术后3 个月复查5 例(62.5%)已恢复正常水平；空腹血糖自术后1 月开始与术前相比差异即有统计学意义（P＜0.01）。结论：腹腔镜袖状胃切除术是一种安全、有效的治疗肥胖症合并T2DM 的手术方式。

英文摘要:

ABSTRACT Objective:To evaluate the short-term effect of laparoscopic sleeve gastrectomy (LSG) on obesity patients with type 2 diabetes mellitus(T2DM). Methods:8 obesity patients with T2DMunderwent LSG surgery from the 3rd department of general surgery of Shanghai Changzheng hospital during July 2008 to December 2011 were included, their clinical data before and after surgery were analyzed retrospectively.Results: All the performations were completed under laparoscopy. There were no conversion or operative complications. There were no serious post-procedure complications. During 12 months of follow-up，all the patients'weight and body mass index (BMI) was decreased, compared with those before operation (P＜0.01). 12 months after procedure, 4（50%）T2DMcases got complete remission, the other4 (50%）cases got partial remission. The level of hemoglobin A1c (HbA1c) and fasting plasma glucose (FPG) was significantly decreased after procedure (P＜0.01) since 1 month after procedure, and 3 months later, the HbA1c level of 5 (62.5%) patients had come back to the normal range.Conclusion: LSG may result in satisfactory weight loss and clinical remission of T2DMwith few complications. A longer follow-up period is needed.

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