| 张敏 赵菁莉.中医药防治腹膜纤维化的研究进展[J].,2014,14(1):166-168 |
| 中医药防治腹膜纤维化的研究进展 |
| The Research Progress of Using Chinese Medicine onControlling Peritoneal Fibrosis |
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| DOI： |
| 中文关键词: 腹膜纤维化 腹膜间皮细胞 腹膜透析 中医药 |
| 英文关键词: Peritoneal fibrosis Peritoneal mesotheliumcell Peritoneal dialysis Traditional Chinese medicine |
| 基金项目:天津市自然科学基金项目（10JCYBJC12100） |
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| 中文摘要: |
| 腹膜透析是治疗终末期肾脏病较为有效的方法之一，但是腹膜长期暴露于非生理性的腹膜透析液中( 低pH、高浓度葡萄糖
以及高渗透压等)会致腹膜纤维化，从而导致腹膜结构和功能的丧失，这是患者放弃腹膜透析的原因之一。现代药理学实验证明，
中医药对于腹膜纤维化的防治研究主要集中在腹膜间皮细胞的上皮间质转化方面，通过对细胞因子的作用，保护和/ 或改善腹膜
间皮细胞的功能防治腹膜纤维化。 |
| 英文摘要: |
| Peritoneal dialysis is one of the effective way of treating end-stage kidney diseases,but the peritoneal that exposures
in the Peritoneal dialysis fluid of Non physiological long terms ( low pH, High concentration of glucose and High osmotic pressure )can
make the patients cause the Peritoneal fibrosis, further lead to the loss in the structure and function of the peritoneal,this is one of the
reasons that the patients give up the Peritoneal dialysis. Modern pharmacology experiment prove that The Research Progress of using
Chinese Medicine on controlling Peritoneal Fibrosis mainly concentrate on Peritoneal mesothelium cell epithelium interstitial
transformation, By the effect on the cell factor, protecting and/or improving the peritoneal mesothelium cell function control peritoneal
fibrosis. |
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