| 李永鸿赵旭巫碧佳王鹏李荣.进展性卒中血同型半胱氨酸变化的相关研究[J].,2012,12(27):5316-5318 |
| 进展性卒中血同型半胱氨酸变化的相关研究 |
| A Study of the Blood Homocysteine Variational of Stroke in Progression |
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| DOI： |
| 中文关键词: 同型半胱氨酸 进展性卒中 TOAST 分型 |
| 英文关键词: Homocysteine Stroke in progress TOAST classification |
| 基金项目:佛山市科技局资助项目（201008092） |
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| 中文摘要: |
| 目的：了解各型SIP 患者Hcy 浓度改变特点的同时，更深一层地探讨各型进展性卒中病情变化与血Hcy 水平的关系。方法：
抽取SIP 组、SIS 组脑卒中患者各50 名，发病第1，2，3 天清晨空腹肘静脉血5 mL，采用全自动快速分析仪及其配套Hcy 试剂盒，
用荧光偏振免疫法测定血浆总Hcy 水平。结果：不论是进展性脑卒中还是稳定性脑卒中，与正常相比，Hcy 的水平要高于正常组，
差异具有显著性，P<0.01；同时进展性脑卒中与稳定性脑卒中相比较而言，进展性脑卒中的Hcy 水平显著高于稳定性脑卒中，P<0.
05。结论：SIP 患者Hcy 水平显著高于稳定性脑卒中，Hcy 增高可能是SIP 发展的一个标志。 |
| 英文摘要: |
| Objective: To investigate the characteristics of the plasma homocysteinemia (Hcy) concentration in stroke in progress
(SIP), and to further explore the relationship between plasma Hcy level and disease condition changes of stroke in progress. Methods:
5ml fasting venous blood were drawn each from 50 SIP patients and 50 SIS patients at the first day, the second day and the third day of
attack. Then the plasma Hcy concentrations were measured by using fluorescence polarization immunoassay (FPLA ) with full-automatic
speedy analyser and its matched Hcy kits. Results: Plasma Hcy concentrations in patients with SIP or SIS were significantly higher than
that in the control group (P<0.01). The plasma Hcy concentrations of patients with SIP were also higher than that of patients with SIS
(P<0.05). Conclusion: SIP patients had obviously higher plasma Hcy concentrations than SIS patients. The increase of Hcy concentration
may be a sign of the SIP development. |
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