| 闫晓红刘尧耿熠.金龙胶囊联合化疗治疗晚期非小细胞肺癌临床疗效观察[J].,2012,12(25):4878-4881 |
| 金龙胶囊联合化疗治疗晚期非小细胞肺癌临床疗效观察 |
| Jin Long Capsule Combined with NP Chemotherapy in the Treatmentof Advanced NSCLC Patients |
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| DOI： |
| 中文关键词: 金龙胶囊 NP 晚期非小细胞肺癌 治疗效果 生活质量 |
| 英文关键词: Jin Long Capsule NP Advanced Non-small Cell Lung Cancer Therapeutic Effect Quality of Life |
| 基金项目:国家自然科学基金项目（30770823） |
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| 中文摘要: |
| 目的：观察金龙胶囊联合化疗与单纯化疗对晚期肺小细胞癌患者的疗效、生活质量等因素的影响。方法：将99 例患有晚期
非小细胞肺癌患者随机分为两组：治疗组，在NP 化疗方案基础上加服金龙胶囊治疗；对照组，单纯接受NP 方案化疗。对99 例患
者追踪2 个月，观察并比较患者的疗效、体质量、生活质量、毒副反应等方面的差异。结果：在NP 化疗方案基础上加服金龙胶囊治
疗在患者疗效评价方面与单纯NP 方案化疗相比不具有统计学差异（P>0.05）；在提高患者体质量、改善患者临床症状和生活质量
等方面均优于单纯NP 方案化疗(P<0.05)；在化疗所引发的白细胞、血红蛋白和血小板降低等部分毒副反应发生率方面低于单纯
NP 方案化疗组（P<0.05）。结论：金龙胶囊联合NP 化疗治疗晚期非小细胞肺癌不仅可以起到化疗增效的作用，而且能够明显提高
患者生活质量，有效的改善临床症候，降低化疗引发的毒副反应，这一联合治疗方案可以在临床治疗中广泛推广。 |
| 英文摘要: |
| Objective: To observe the differences between pure chemotherapy and Jin Long capsule combination with chemotherapy
treatment for patients' therapeutic effect and the quality of life with advanced non-small cell lung cancer (NSCLC) patients. Methods: 99
cases advanced NSCLC patients were randomly divided into chemotherapy group and Jin Long capsule combination with chemotherapy
group. Chemotherapy group was treated with NP scheme (vinorelbine, NVB and cis-platinum, DDP). At the same time, the other group
was treated with Jin Long capsule and NP scheme. All patients were observed for two months and analyzed the differences in the therapeutic
effect score, body quality score, quality of life score and toxic effect. Results: Jin Long capsule combination with NP scheme is superior
to NP scheme in the improvement of body quality score, quality of life score and the decrease of toxic effect (P< 0.05). However,
the combined scheme is not better than NP scheme in the improvement of therapeutic effect score (P>0.05). Conclusion: Jin Long capsule
combination with NP scheme could improve the life quality and body quality of the patients and decrease the incidence of toxic effect
induced by chemotherapy. |
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