邓颖慧陆海波△.胆道系统恶性肿瘤的内科治疗新进展[J].,2012,12(24):4791-4796 |
胆道系统恶性肿瘤的内科治疗新进展 |
New Progress in Medical Treatment of Biliary Tract Carcinoma |
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DOI: |
中文关键词: 胆道系统 恶性肿瘤 化疗 进展 |
英文关键词: Biliary system Cancer Chemotherapy Progress |
基金项目: |
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中文摘要: |
胆道系统恶性肿瘤是一种发病率低、预后差的肿瘤,包括胆管癌、胆囊癌及壶腹部癌。在西方国家胆道系统恶性肿瘤大约占
胃肠道肿瘤的4%,东南亚发病率相对较高。在我国,胆道系统恶性肿瘤的发病率并没有明确数字,约占消化道肿瘤的第6 位。胆
系肿瘤生存率低,预后差,至今尚无有效的化疗方案。目前,关于进展期胆系肿瘤化疗的Ⅱ、Ⅲ期临床试验研究以逐渐开展,化疗
方案以吉西他滨为主,单药或联合铂类等药物,得到了明显提高的有效率及生存期。本文就目前胆系肿瘤化疗方面新的进展及成
果做综述。 |
英文摘要: |
Biliary tract carcinoma is a low incidence and poor prognosis tumor. It includes cholangiocarcinoma, gallbladder and
ampullary carcinoma. In Western countries, biliary system cancer accounts for about 4% of gastrointestinal cancer, this incidence is relatively
high in Southeast Asia. In China, the incidence of biliary malignancies has no clear figures and Accounting for 6 of the digestive
tract tumors. Biliary tract cancer low survival rate and poor prognosis, so far there is no effective chemotherapy. At present, about advanced
biliary tract cancer chemotherapy, II, III clinical trials research to gradually carry out ,has been significantly improved efficiency
and lifetime. Chemotherapy with gemcitabine-based, single agent or in combination with platinumdrugs. This article review on biliary
tract cancer chemotherapy, new progress and achievements. |
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