| 吴海云1,3 刘志兰2△ 王丹1 刘芳1 张磊1.扩散张量成像对颈椎病脊髓早期损伤的研究[J].,2012,12(22):4342-4346 |
| 扩散张量成像对颈椎病脊髓早期损伤的研究 |
| Research the Value of Diffusion Tensor Imaging in Cervical SpinalCord Earlier Injury |
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| DOI： |
| 中文关键词: 脊髓压迫 颈椎椎间盘突出 磁共振成像 扩散张量成像 |
| 英文关键词: Spinal cord compression Cervical prolapsed vertebral disc Magnetic resonance imaging Diffusion tensor imaging |
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| 中文摘要: |
| 目的：探讨磁共振(MR)扩散张量成像(DTI)作为定量分析方法，对脊髓型颈椎病(CSM)脊髓早期损伤诊断的应用价值。方法：
选择45 例经临床及影像诊断为脊髓型颈椎病患者，颈椎常规MRI 检查显示脊髓内无异常信号，使用单次激发自旋回波平面
(SE-EPI)序列，进行DTI 扫描。测量压迫部位脊髓的ADC 值及FA 值作为病例组，选择病变上或下方两个节段以上未受压正常脊
髓作为正常对照组，测量其ADC 值及FA 值。分析病例组与对照组间ADC 及FA 值差别，计算ADC 值及FA 值诊断脊髓损伤的
敏感性。结果：所有脊髓型颈椎病患者经DTI 检查均可得到ADC 图及FA 图，经图像后处理，脊髓显示清晰，图像无变形及伪影。
3 例脊髓型颈椎病患者ADC 值降低，42 例脊髓型颈椎病患者ADC 值增高，平均ADC 值为(1.388±0.149)×10-3 mm2/s。44 名脊
髓型颈椎病患者FA 值降低，1 名脊髓型颈椎病患者FA 值增高，平均FA 值为0.476±0.085，受压处脊髓平均ADC 值升高，平均
FA 值下降，与正常值比较差别有统计学意义。ADC 值诊断的敏感性为93.33 %，FA 值诊断的敏感性为97.78 %。结论：DTI 与常规
MR 比较，能早期而准确地诊断脊髓型颈椎病脊髓早期损伤。 |
| 英文摘要: |
| Objective: To investigate the magnetic resonance diffusion tensor imaging (DTI) in the diagnosis of cervical spondylotic
myelopathy (CSM), which was a quantitative analysis method. Method: Clinical and imaging diagnosed 45 patients who have cervical
spondylosis enter this experiment. Conventional cervical MRI revealed no abnormal signal in the spinal cord. These 45 cases were
examined with routine MRI and DTI on MR scanner using single shot echo planar imaging (SE-EPI) sequences. ADC and FA values of
the parts of spinal cord compression were measured. Selected lesions above or below the two segments in the normal Spinal cord as a
normal control group, Analysis the differences in ADC and FA values between cases and control groups, then calculate the sensitivity of
the ADC and FA values in the diagnosis of spinal cord injury. Results：All cervical spondylosis cases completed the examinations without
obvious artifacts on the diflusion tensor images. Three cases had decreased ADC values, forty-two patients had increased ADC values,
the mean ADC value were (1.388±0.149)×10-3 mm2/s, forty-four patients had decreased FA values, one patient with FA values
increased, the average FA value were 0.476±0.085. The mean ADC value of compression at the cervical spinal cord increases, the
average FA value decreased, there were significant differences compared with normal group. The diagnostic sensitivity of ADC and FA
values are 93.33 %, 97.78 %. Conclusion: Compared with conventional MR, DTI can accurately diagnose the cervical spondylotic
myelopathy of cervical spinal cord earlier injury. |
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