| 廖礼彬1 吐尔逊江·达地汗2 古丽尼沙·克力木2△ 郭莲萍3 王水泉2.新疆医科大学基础医学院组织胚胎学教研室[J].,2012,12(19):3610-3613 |
| 新疆医科大学基础医学院组织胚胎学教研室 |
| Electron Microscopic Observations of Trigeminal Ganglion CellsDifferentiation in Chinese Fetus |
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| DOI： |
| 中文关键词: 三叉神经节细胞 电镜 人胚胎 |
| 英文关键词: Trigeminal ganglion cells Electron microscopic Human fetus |
| 基金项目:国家自然科学基金项目(30960157) |
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| 中文摘要: |
| 目的：观察国人胚胎三叉神经节细胞分化及发育过程。方法：取水囊引产18-36 周国人胎儿三叉神经节，HE 染色及透射电镜
观察。结果：18-20 周胎儿三叉神经节神经元排列紧密，胞质少，可见到数量不多的线粒体，且其内几乎看不到嵴，其它细胞器少。
25 周时，线粒体嵴变长，粗面内质网雏形出现，有纵形小管出现；27 周时可观察到成熟的高尔基复合体，32 周后，线粒体、粗面内
质网等细胞器发育趋于成熟。到33 周电镜下可见溶酶体；36 周时细胞内各种细胞器结构和功能基本完善。结论：人胚胎三叉神经
节细胞发育过程中随胎龄增加，其结构和功能逐步完善，32～36 周（8～9 月）是细胞的分化发育重要时期。 |
| 英文摘要: |
| Objective: To investigate the development and differentiation of human fetus trigeminal ganglion cells with the age
increased. Methods: Chinese human trigeminal ganglia were obtained from 18-36 weeks old abortion fetuses, and the ultrastructural
changes of cells were detected by using optical and transmission electron microscope. Results: After 18 to 20 weeks' development, the
neurons in the trigeminal ganglion cells tightly packed, with little cytoplasm and can observe a small number of mitochondria which is
barely seen the cristae, there were few other organelles, 25 weeks, mitochondria cristae became longer , rough endoplasmic reticulum
shape appeared, some showed a longitudinal tubules, the mature Golgi complex appeared at 27 weeks old fetus. After 32 weeks, the
development of mitochondria, rough endoplasmic reticulum and other organelles approached maturity; the lysosome can be seen under
electron microscope until 33 weeks; At 36 weeks, the structure and function of all kinds of intracellular organelles basically have
completely developed. Conclusion: The structure and function gradually improved with gestational age increased during human fetal
trigeminal ganglion cells development, 32 to 36 weeks (8 ~ 9 months) was an important period of cells differentiation and development. |
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