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目的：探讨净石灵胶囊联合体外冲击波碎石术治疗复杂性肾结石临床疗效。方法：选取2010 年1 月- 2011 年12 月在我院就诊的复杂性肾结石患者83 例，随机分为体外冲击波碎石术组、经皮肾镜碎石取石组、净石灵胶囊联合体外冲击波碎石术组。观察两组间的手术时间、碎石率、疗效以及组内之间不同直径的结石的碎石率。结果：ESWL 组碎石成功率85.3%，PCNL 组碎石成功率90.0%，净石灵胶囊联合体外冲击波碎石术组碎石成功率89.7%，三组比较无统计学意义（P>0.05）；ESWL 组手术时间（40.2±6.3）min，PCNL 组手术时间（46.6±4.1）min，净石灵胶囊联合体外冲击波碎石术组手术时间（42.2±5.7）min，三组比较无统计学意义（P>0.05）；ESWL 组、PCNL 组、净石灵胶囊联合体外冲击波碎石术组治疗复杂性肾结石的有效率依次为75.0%、80.0%、 97.4%，组间比较，差异具有统计学意义（P<0.05）；ESWL 组5<10mm、10<15mm、15<20mm 直径的肾结石的粉碎率依为100%、 85.7%、40%，组内比较具有统计学意义（P<0.01），PCNL 组5<10mm、10<15mm、15<20mm 直径的肾结石的粉碎率依次为100%、 83.3%、75%，组内比较具有统计学意义（P<0.05），净石灵胶囊联合体外冲击波碎石术组5<10mm、10<15mm、15<20mm 直径的肾结石的粉碎率依次为100%、88.9%、57.1%，组内比较具有统计学意义（P<0.01）。结论：体净石灵胶囊联合体外冲击波碎石术治疗复杂性肾结石的临床疗效优于单纯运用体外冲击波碎石术或经皮肾镜碎石取石术。

英文摘要:

Objective: To explore the clinical effect of Jing Shi Ling capsule combined with Extracorporeal Shock Wave Lithotripsy on complicated renal stone. Methods: 83 patients with renal stone selected from June 2010 to December 2011 in our hospital were randomly divided into ESWL group, PCNL group and Jing Shi Ling capsule combined with ESWL group. The operation time, the renal stone free rate and the therapeutic rate are observed, as well as the fragmentation rate of stones in different diameters in a group. Results: The stone free rate of the ESWL group, PCNL group and Jing Shi Ling capsule Combined with ESWL group was 85.3%, 90.0%, 89.7% respectively, so there is no statistical difference between the three groups (P>0.05). The operation time of the three groups was respectively (40.2±6.3) min, (46.6±4.1) min, and (42.2±5.7) min, with no statistical difference(P>0.05). The therapeutic rate of the ESWL group, PCNL group and Jing Shi Ling capsule with ESWL group was 75.0%, 80.0%, 97.4% respectively; there was statistical difference between the three groups ( P<0.05). The fragmentation rate of the complicated renal stone in the ESWL group with the diameter 5~10mm, 10~15mm, 15~20mm is 100%, 85.7%, 40% respectively, with statistical difference(P<0.01); the fragmentation rate in the PCNL group with the diameter 5~10mm, 10~15mm, 15~20mm is 100%, 83.3%, 75% respectively, showing statistical difference (P<0.05); the fragmentation rate of the complicated renal stone in the Jing Shi Ling capsule with ESWL group with the diameter 5~10mm, 10~15mm, 15~20mm is 100%, 88.9%, 57.1% respectively, also with statistical difference(P<0.01). Conclusion: ESWL, PCNL and Jing Shi Ling capsule with ESWL all are effective to treat complicated renal stone; Jing Shi Ling capsule with Extracorporeal Shock Wave Lithotripsy have a better clinical effect than the ESWL or PCNL in treating complicated renal stone.

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