| Venenum Bufonis, the name of which origin from the Canon of Chinese Materia Medica Ben Cao Yan Yi, is a rare
and valuable traditional Chinese medicine. It is widely applied in clinic, for it contains many chemical components and has functions in
analgesia, strong heart, boosting pressure, local anesthesia, anti-inflammatory and antitumor. The active antitumor component of venenum
bufonis is bufogenin compound, including bufogenin, cinobufagin, bufalin and so on. The antitumor activity mainly includes inducing
apoptosis of tumor cells, inhibiting the cell proliferation and inducing the cell differentiation. In recent years, the antitumor effects of
venenum bufonis and its active components has become research focus at home and abroad. |
