| 韩军勇高永华.治疗肝纤维化的蛋白质药物研究进展[J].,2012,12(13):2596-2600 |
| 治疗肝纤维化的蛋白质药物研究进展 |
| The Development of Protein Agents inTreatment of Liver Fibrosis |
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| DOI： |
| 中文关键词: 肝纤维化 蛋白质药物 细胞外基质 肾素- 血管紧张素系统 抗氧化 抗炎 免疫调节 细胞因子 |
| 英文关键词: Liver fibrosis Protein drug ECM RAS Antioxidation Anti- inflammatory Immunoloregulation Cytokine |
| 基金项目: |
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| 中文摘要: |
| 肝纤维化是肝脏出现瘢痕组织，瘢痕尽管在肝脏的位置有异，但是均一致表现为细胞外基质的增生和性质转变，尤其在疾病
的早期。蛋白质药物在治疗疾病方面有许多优势，我们将用于治疗肝纤维化的蛋白质药物做出总结，为新药研究提供思路。 |
| 英文摘要: |
| Liver fibrosis is the presence of scar tissue in the liver. Although it varies in location within the liver, especially in
early disease, the liver scar uniformly represents both an excess of extracellular matrix (ECM) and a shift in the quality of that matrix.
Protein drug have lots of advantages in cure disease, so we conclude protein drugs in liver fibrosis'therapy, in order to provide ideas to
new drug research. |
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