| 黎人铚1 张俊1 张杰伟2 张全鹏3.雷贝拉唑联合莫沙必利治疗反流性食管炎的临床疗效观察[J].,2012,12(11):2131-2133 |
| 雷贝拉唑联合莫沙必利治疗反流性食管炎的临床疗效观察 |
| The Efficacy of Rabeprazole Combined with Mosapride in the Treatmentof Reflux Esophagitis |
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| DOI： |
| 中文关键词: 雷贝拉唑 奥美拉唑 食管炎 |
| 英文关键词: Rabeprazole Omeprazole RE |
| 基金项目: |
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| 中文摘要: |
| 目的：治疗雷贝拉唑联合莫沙必利治疗返流性食管炎的临床疗效。方法：108 例反流性食管炎患者随机分成两组，治疗组56
例和奥美拉唑对照组52 例，治疗组应用雷贝拉唑和莫沙必利，对照组应用奥美拉唑和莫沙必利，观察治疗前后患者的临床症改
善和内镜变化。结果：治疗8 周，治疗组症状积分明显优于对照组(P<0.05)，治疗组疗效明显优于对照组(P＜0.05)，胃镜检查结果
示治疗组食管黏膜愈合情况优于对照组(P＜0.5)。结论：雷贝拉唑和莫沙必利联用治疗反流性食管炎临床症状明显改善，联合用药
临床疗效优于奥美拉唑。 |
| 英文摘要: |
| Objective: To observe the efficacy of rabeprazole combined with mosapride in the treatment of reflux esophagitis
(RE). Methods: 108 cases of RE was randomized to two groups, 56 cases in treatment group and 52 cases in control group. The treatment
group was treated with rabeprazole and mosapride. The control group was treated with omeprazole and mosapride. The change in symptom
and endoscope before and after treatment were observed. Results: After treated for 8 weeks, the score of symptom had been improved obviously
in treatment group (P<0.05). And the total effective rate was better in treatment group than control group (P<0.05). Esophageal
mucosa concrescence was significantly better in treatment group. There was difference between the two groups(P<0.05). Conclusion: The
clinical symptoms of RE were markedly improved after treatment of rabeprazole combined with mosapride. Its efficacy is better than that
of omeprazole combined with mosapride. |
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