文章摘要
黄承乐黄红华黄荣幸农世泽岑柳仙.IL-6,IL-8 的检测在鉴别良恶性胸水中的诊断价值分析[J].,2012,12(9):1707-1709
IL-6,IL-8 的检测在鉴别良恶性胸水中的诊断价值分析
Differential Diagnostic Value of Determination of IL-6, IL-8 in Serum andPleural Effusion between Benign and Malignant Hydrothorax
  
DOI:
中文关键词: 白细胞介素6  白细胞介素8  胸水  诊断价值
英文关键词: IL-6  IL-8  Hydrothora  Differential diagnostic value
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作者单位
黄承乐黄红华黄荣幸农世泽岑柳仙 广西壮族自治区百色市人民医院 
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中文摘要:
      目的:分析检测血清、胸水中白细胞介素6(IL-6)、白细胞介素8(IL-8)水平对良恶性胸水的鉴别诊断价值。方法:采用酶联免 疫吸附试验(ELISA)检测32 例良性胸水患者和40 例恶性胸水患者血清及胸水中IL-6、IL-8 水平,以及30 例健康体检者血清中 IL-6、IL-8 水平。结果:良性胸水组及恶性胸水组血清IL-6、IL-8 水平均显著高于正常对照组,差异具有统计学意义(P<0.05);与恶 性胸水组比较,良性胸水组胸水及血清中IL-6、IL-8 水平升高更为显著(P<0.05),良性胸水组IL-6、IL-8 的胸水/ 血清比值也显著 高于恶性胸水组,差异具有统计学意义(P<0.05)。结论:胸水及血清中IL-6、IL-8 的检测对良、恶性胸水患者具有鉴别诊断意义。
英文摘要:
      Objective: To explore the differential diagnosis value of determination of IL-6, IL-8 in serum and pleural effusion between benign and malignant hydrothora. Methods: The levels of IL-6, IL-8 in serum and pleural effusion of 32 cases with benign hydrothorax, 40 cases with malignant hydrothora were detected, and the levels of IL-6, IL-8 in serum of 30 healthy subjects were detected by ELISA. Results: The levels of IL-6, IL-8 in serum were significantly increased in cases with benign or malignant hydrothora in comparison with those of control group, the difference was statistically significant (P<0.05). There were statistically significant differences of the levels and the pleural effusion/serum ratio of IL-6, IL-8 in serum and pleural effusion between benign and malignant hydrothora (P>0.05). Conclusion: The levels of IL-6, IL-8 in serum and pleural effusion may be used as an marker in the differential diagnosis of benign and malignant hydrothora.
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