| 李之珍胡晓武许霞杨飞孙晓祥.糖化血红蛋白与糖尿病及其并发症的关系[J].,2011,11(21):4123-4125 |
| 糖化血红蛋白与糖尿病及其并发症的关系 |
| The Value of Glycosylated Hemoglobin 1c Detection in Diagnosisand Complications of Diabetes in Diabetes |
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| DOI： |
| 中文关键词: 糖化血红蛋白 糖尿病 空腹血糖 餐后2 h血糖 |
| 英文关键词: Glycated hemoglobin Diabetes Fasting plasma glucose 2 hour plasma glucose |
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| 中文摘要: |
| 目的：探讨糖化血红蛋白（HbAlc）与糖尿病诊断、疗效评价及并发症的关系。方法：选择2 型糖尿病患者250 例和健康体检
者150例，分别测定空腹血糖( FPG) 、2 h 血糖( 2hPG ) 及糖化血红蛋白( H bA1c)，统计学分析HbA1c 与FPG、2hPG 的相关性；分
析HbA1c 与糖尿病并发症发生的关系。结果：糖尿病组FPG、2hPG及H bA1c 水平均显著高于对照组(P< 0. 01)；糖尿病伴有并发
症患者的HbAlc 明显高于无并发症者（P<0.05），H bA1c 水平与糖尿病并发症的发生率存在高度相关性( P <0. 01)。结论：检测外
周血中H bA1c 水平对2型糖尿病诊断、疗效评价具有重要临床价值，控制糖化血红蛋白对预防糖尿病并发症的发生具有重要意
义。 |
| 英文摘要: |
| Objective: To investigate the Glycosylated hemoglobin1c (HbA1c) test for diagnosis of diabetes, efficacy evaluation
and prediction of complications in clinical value. Methods: Choose patients with type 2 diabetes mellitus (T2DM group) 250 cases and
healthy subjects ( control group) 150 patients, measured by fasting plasma glucose(FPG) , 2 hour plasma glucose ( 2hPG ) and glycated
hemoglobin ( HbA1c), then compared analysis of HbA1c and FPG, 2hPG relationship, and analyzed the relationship between HbA1c and
the diabetes related complications. Results: Diabetes group FPG, 2hPG and HbA1c were significantly higher than control group (P < 0.
01); H bA1c levels in the diabetic complications group were significantly higher than patients with no complications (P < 0. 05). There
were high correlation between H bA1c level and the incidence of complications of diabetes (P <0. 01). Conclusion: Detection of H bA1c
levels in diabetic patients has important clinical value in the diagnosis, evaluation of efficacy, and it was important to control the glycated
hemoglobin levels for the prevention of diabetes complications. |
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