李艳1,2 黄晓俊1,2,3△ 陈平1,2,3.DNA 甲基化及其与胃癌相关研究进展[J].,2011,11(18):3577-3579 |
DNA 甲基化及其与胃癌相关研究进展 |
Development Research Of DNA Methylation in Gastric Cancer |
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DOI: |
中文关键词: DNA 甲基化 胃癌 CpG 岛 |
英文关键词: DNA methylation Gastric cancer CpG island |
基金项目: |
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中文摘要: |
DNA 甲基化是表观遗传学中的研究热点,与肿瘤的发生、发展、诊断、治疗、预后等相关。胃癌的发生、发展与DNA 甲基化状
态改变关系密切,研究胃癌相关基因DNA 甲基化状态的改变有助于胃癌的早期发现、诊断、治疗及预后。因此,研究胃癌相关基
因的甲基化状态具有一定的临床价值。 |
英文摘要: |
The research of DNA methylation research was a topic spot in epigenetics, which was associated with the occurrence,
development, diagnosis, treatment and prognosis of tumor. And gastrical tumorigenesis was closely related with DNA methylation status
change, some study suggested that the changes of DNA methylation state of gastric cancer related gene will contribute to early examination,
diagnosis, treatment and prognosis of gastric cancer. |
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