| 舒博杜新香陈鹏毕兴申钧.肾细胞癌淋巴结转移预测指标的Logistic 回归分析[J].,2011,11(18):3527-3530 |
| 肾细胞癌淋巴结转移预测指标的Logistic 回归分析 |
| Prediction of Lymph Node Metastasis in RenalCellCarcinoma by BinaryLogistic Regression |
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| DOI： |
| 中文关键词: 肾肿瘤 淋巴结转移 危险因素 回归分析 |
| 英文关键词: Renal cell carcinoma Lymph node metastasis Risk factors Regression analysis |
| 基金项目: |
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| 中文摘要: |
| 目的：研究肾细胞癌淋巴结转移的危险因素，并建立Logistic 回归模型。方法：2002 年2 月～2010 年10 月我院手术治疗的
肾细胞癌163 例，对其临床病理资料进行单因素和多因素的Logistic 回归分析。结果：淋巴结转移的发生率为20.9%（34/163）。单
因素分析显示：肿瘤大小、临床分期、Fuhrman 核分级和贫血与肾细胞癌淋巴结转移的风险有关（P＜0.05）；多因素分析显示：肿瘤
大小、临床分期和Fuhrman 核分级是RCC 淋巴结转移独立的风险因素。结论：肾细胞癌淋巴结转移的风险与肿瘤大小、临床分期
和Fuhrman 核分级有关，Logistic 回归模型对于判断预后、指导术后治疗及随访方案的制订具有重要作用。 |
| 英文摘要: |
| Objective: To study the risk factors of lymph node metastasis of renal cell Carcinoma （RCC）and to set up a Logistic
regression model. Methods: The clinical data of 163 patients with renal cell carcinoma who underwent radical nephrectomy from 2002 to
2010 in Affiliated Tumor Hospital of Xinjiang Medicial University, were analyzed by univariate and binary Logistic regression. Results:
The incidence of lymph node metastasis was 20.9%. Univariate logistic analysis revealed that the tumor size，clinical stage, Fuhrman nuclear
grade and anemia were all correlated with lymph node metastasis of RCC （P＜0.05）. Binary logistic analysis found that the tumor
size（OR=1.828,P＜0.01）, clinical stage（OR=6.296, P＜0.01）and the Fuhrman nuclear grade（OR=0.377, P＜0.05）were the independent
risk factors responsible for lymph node metastasis of RCC. Conclusion: The risk factors for lymph node metastasis in patients with renal
cell carcinoma were correlated with the tumor size, clinical stage and Fuhrman nuclear grade, The Logistic regression model may be useful
for prognosis and making the postoperative treatment and follow-up program for patients with RCC. |
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