文章摘要
史艳明张弛△ 李华珠杨晓春周桂莲王敏吴文宇熊璞王霞陈晶.阻塞型睡眠呼吸暂停低通气综合征与代谢综合征组分关系探讨[J].,2011,11(18):3472-3475
阻塞型睡眠呼吸暂停低通气综合征与代谢综合征组分关系探讨
The Relationship between Obstructive Sleep Apnea HypoventilationSyndrome and Components of Metabolic Syndrome
  
DOI:
中文关键词: 阻塞性睡眠呼吸暂停综合征  代谢综合征  肥胖  高血脂
英文关键词: Obstructive sleep apnea syndrome  Metabolic syndrome  Obesity  Hyperlipidemia
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作者单位
史艳明张弛△ 李华珠杨晓春周桂莲王敏吴文宇熊璞王霞陈晶 湖南省人民医院湖南师范大学第一附属医院内分泌科 
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中文摘要:
      目的:探讨阻塞型睡眠呼吸暂停低通气综合征(OSAHS)与代谢综合征(MS)组分关系。方法:对我院2003 年1 月至2010 年 7 月39 例诊断为OSAHS 住院患者进行回顾性调查,30 例同期住院病人为对照组,均记录年龄、性别,测量身高、体重、血压,检测 空腹血糖、血脂,分析OSAHS 患者合并MS 组分情况。结果:1.OSAHS 组与对照组比较,体重指数(BMI)、血压、血清甘油三酯、总 胆固醇、低密度脂蛋白胆固醇、载脂蛋白A1 升高,高密度脂蛋白胆固醇降低(P<0.05);2.OSAHS 组与对照组相比较,无MS 组分 比例低于对照组,差异有统计学意义(P<0.05);3.OSAHS 组与对照组相比较,OSAHS 组合并MS 组分,包括BMI≥25Kg/m2,血 脂紊乱的比例,均高于对照组,差异有统计学意义(P<0.05)。结论:OSAHS 患者易合并代谢综合征组分。
英文摘要:
      Objective: To explore the relationship between obstructive sleep apnea hypopnea syndrome (OSAHS) and components of metabolic syndrome (MS). Methods: 39 cases of hospitalized patients diagnosed with OSAHS were studied retrospectively from January 2003 to July 2010. 30 cases of hospitalized patients at the same time with no OSAHS were collected as control group. Age, sex, body height, body weight, blood pressure, fasting blood glucose, lipid profile were recorded. Results: 1. The body mass index (BMI), blood pressure, serum triglyceride, total cholesterol, low-density lipoprotein cholesterol, apolipoprotein A1 were higher and low-density lipoprotein cholesterol were lower in patients with OSAHS than in controls (P<0.05). 2. The prevalence of those without any components of MS in OSAHS was lower than controls (P<0.05). 3. The prevalence of those with combined components of MS, including BMI≥ 25kg/m2 and lipid disorders was higher in OSAHS group than in control group. (P<0.05). Conclusions: Patients wtith OSAHS were proned to develope components of MS.
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