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目的：探讨微波高温灭活及自体髂骨、异体骨粒复合骨水泥修复骨巨细胞瘤病灶刮除后骨缺损的临床应用效果。方法：应用原位分离插入式微波天线高温灭活技术，自体髂骨、异体骨粒复合骨水泥修复21 例长骨骨巨细胞瘤术后骨缺损，从手术技术、肿瘤复发情况、肢体关节功能等方面全面综合评价此方法临床应用效果。结果：21 例患者均获得骨性愈合，无骨折及内固定断裂发生，2 例复发，复发率9.8%；肢体关节功能优18 例（85.7%）、良3 例（14.3%）、中差0 例。结论：微波高温能彻底杀灭肿瘤组织降低复发率，自体髂骨保证与近关节软骨下骨愈合，异体骨粒复合骨水泥能良好充填残余瘤腔、且具有良好的生物力学性能，以防发生关节软骨面塌陷。

英文摘要:

Objective: To evaluate the effectiveness of microwave hyperthermia for the treatment of giant cell tumor of long bone, followed by reconstruction of resulted bone defect with compound including self-ilium, allogeneic bone powders and bone cement. Methods: 21 cases of giant cell tumor of long bone were treated with hyperthermia by inserting microwave antennas after tumor exposure in situ and the resulted bone defect were reconstructed with the compound including self-ilium, allogeneic bone powders and bone cement. The effect of this method was evaluated comprehensively including the applying technology, recurrence rate of tumor and reserved function of limbs and joints. Results: All the cases gained the bone union, none of bone fracture and rupture of internal fixation plate was found. 2 cases recurred, and the recurrence rate was 9.8%. The reserved function of limbs and joints was excellent in 18 cases (85.7%), fine in 3 cases(14.3%), and none poor. Conclusion: Microwave hyperthermia could kill the tumors completely and decrease the rate of tumor recurrence, self-ilium might unite with subchondral bone, and allogeneic bone powders combined with bone cement could fill the resulted cavity to prevent the potential collapse of articular cartilage.

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