| 魏海燕史宏伟张媛.围体外循环期血小板保护的研究进展[J].,2011,11(7):1391-1393 |
| 围体外循环期血小板保护的研究进展 |
| The advance of platelet preservation during cardiopulmonary bypass |
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| DOI： |
| 中文关键词: 体外循环 血小板保护 血小板分离技术 |
| 英文关键词: cardiopulmonary bypass platelet preservation plateletphoresis |
| 基金项目:南京市卫生局科技发展项目（YKK06066） |
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| 中文摘要: |
| 在体外循环过程中，血小板可经各种途径被激活，导致α- 颗粒释放，发生粘附、聚集、收缩、释放等反应，导致术后血小板数
量和质量的下降。通过在围体外循环期使用某些药物可对血小板进行功能性保护，而血小板分离技术可使血小板避免体外循环
的打击，得到数量和功能的双重保护。本文将就体外循环期间血小板保护的研究进展作一综述。 |
| 英文摘要: |
| Platelets can release α -granules when activated by various kinds of factors and then proceed to adhension, aggregation,
contraction and releasing. Therefore, the quantities and qualities of platelets are decreased after cardiac operation. The function of
platelets can be protected by some drugs used during cardiopulmonary bypass. Plateletphoresis can preserve the quantities and function of
platelets by making some platelets avoid cardiopulmonary bypass. This review addresses the advance of platelet preservation during cardiopulmonary
bypass. |
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