文章摘要
宁宇王健.MicroRNA 与胶质瘤的分子病理特征研究进展[J].,2011,11(5):989-991
MicroRNA 与胶质瘤的分子病理特征研究进展
Progresses in MicroRNA and Features of Molecular Pathology of Glioma
  
DOI:
中文关键词: MicroRNA  胶质瘤  分子病理  基因
英文关键词: MicroRNA  glioma  Molecular Pathology  gene
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作者单位
宁宇王健 解放军第251 医院肿瘤科 
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中文摘要:
      MicroRNAs(miRNAs)是一类非编码的内源性小RNA 分子,通过调节mRNA 的稳定性及蛋白翻译过程控制基因表达,从而 发挥促癌或抑癌作用;研究表明,在胶质瘤的发生、进展、侵袭过程中,伴随发生了许多分子病理特征的改变,这一过程中miRNAs 发挥着重要作用,本文就此方面研究进展进行综述。
英文摘要:
      MicroRNAs(miRNAs) is a kind of non-coding endogenous small RNA molecules, which controls gene expression by modulating the stabilities of mRNA and the progression of protein translation, and plays a role in tumor promotion or inhibition; studies show that features of the molecular pathology of glioma change a lot in the progress of tumor genesis,progression and invasion, in which miRNAs play an important role, this article reviewed the progresses of the research that concerned.
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