Objective:To investigate the correlation between blood lipid, platelet parameters, homeostasis model insulin resistance index (HOMA-IR) and polysomnography (PSG) parameters in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) complicated with hypertension and their predictive value. Methods:163 patients with OSAHS who were admitted to Shuyang Hospital Affiliated to Xuzhou Medical University from January 2020 to November 2022 were selected, and they divided into simple OSAHS group (78 cases) and hypertension group (85 cases) according to whether they were combined with hypertension. Blood lipid, platelet parameters and HOMA-IR, PSG parameters in the two groups were measured. Pearson correlation analysis was used to analyze the correlation between blood lipid, platelet parameters, HOMA-IR and PSG parameters. Multivariate Logistic regression analysis was used to analyze the risk factors of OSAHS complicated with hypertension. The receiver operating characteristic (ROC) curve was used to analyze the value of blood lipid, platelet parameters and HOMA-IR in predicting OSAHS complicated with hypertension.Results:Triglycerides (TG), Total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), mean platelet volume (MPV), HOMA-IR, micro arousal index (MAI), apnea hypopnea index (AHI) and oxygen Reduction Index (ODI) in the hypertension group were higher than those in the simple OSAHS group (P<0.05), high-density lipoprotein cholesterol (HDL-C) was lower than that in the simple OSAHS group (P<0.05). The TG, TC, LDL-C, MPV, HOMA-IR in the hypertension group were positively correlated with MAI, AHI and ODI (P<0.05), while HDL-C was negatively correlated with MAI, AHI and ODI (P<0.05). High body mass index, high HOMA-IR, TG and MPV levels were the risk factors for patients with OSAHS complicated with hypertension (P<0.05). The area under the curve of OSAHS patients with hypertension predicted by combining TG, MVP and HOMA-IR was higher than that predicted by the above three indicators alone.Conclusion:The TG, MPV levels and HOMA-IR in patients with OSAHS complicated with hypertension are significantly increased, and are positively correlated with MAI, AHI and ODI. The combined detection of TG, MPV and HOMA-IR has a higher predictive value for patients with OSAHS complicated with hypertension. |