| Objective:To analyze the influencing factors of enteral nutrition feeding intolerance in patients with severe acute pancreatitis (SAP), and to explore the predictive value of intra-abdominal pressure on it. Methods:80 patients with SAP who were treated in the ICU of Jiangsu Provincial People''s Hospital from January 2018 to January 2021 were selected, and they were treated with enteral nutrition through three lumen nasojejunal tube, and the incidence of enteral nutrition intolerance was counted. The clinical data of all patients were collected, the influencing factors of enteral nutrition feeding intolerance in patients with SAP were analyzed by multivariate Logistic regression, and the predictive value of intra-abdominal pressure on enteral nutrition feeding intolerance in patients with SAP was analyzed by receiver operating characteristic (ROC) curve. Results:The incidence of enteral nutrition feeding intolerance in 80 patients with SAP was 53.75% (43 / 80). Multivariate Logistic regression analysis showed that age ≥ 60 years (OR= 4.679, 95% CI: 1.549 ~ 23.078, P = 0.026), the start time of enteral nutrition ≥ 72h (OR= 7.069, 95% CI: 1.700 ~ 29.395, P = 0.007), and intra-abdominal pressure ≥ 15 mmHg (OR= 4.495, 95% CI: 1.137 ~ 17.770, P = 0.032) were the risk factors of enteral nutrition feeding intolerance in patients with SAP, while albumin ≥ 35g / L (OR= 0.264, 95% CI: 0.073 ~ 0.956, P = 0.042) and added dietary fiber were (OR= 0.178, 95% CI: 0.048 ~ 0.662, P = 0.010) were the protective factor of enteral nutrition feeding intolerance in patients with SAP. The ROC curve analysis showed that the area under the curve of intra-abdominal pressure predicting enteral nutrition feeding intolerance in patients with SAP was 0.809 (95% CI: 0.706 ~ 0.888), the sensitivity was 79.07%, and the specificity was 72.97%. Conclusion:Enteral nutrition feeding intolerance in patients with SAP is related to age, start time of enteral nutrition, intra-abdominal pressure, albumin level and whether to add dietary fiber. Intra-abdominal pressure has a certain predictive value for enteral nutrition feeding intolerance in patients with SAP. |
