Objective: To observe the efficacy of phacoemulsification (PE) combined with intraocular lens implantation (IOL) in the treatment of cataract, and to analyze the influencing factors of postoperative anterior chamber exudation. Methods: 406 cases (482 eyes) of cataract patients who were treated with PE combined with IOL in our hospital from January 2018 to February 2021 were retrospectively analyzed. The changes of visual acuity and postoperative complications were observed. The influencing factors of postoperative anterior chamber exudation were analyzed by univariate and multivariate Logistic regression. Results: The proportion of postoperative visual acuity of 0.6~0.9 and ≥1.0 eyes in cataract patients was higher than that before operation (P<0.05). Postoperative complications occurred in 46 eyes of cataract patients, including lens pigmentation, posterior capsule opacity and corneal edema in 3 eyes, fibrous exudative membrane in 2 eyes and anterior chamber exudation in 35 eyes, respectively, with a complication rate of 9.54% (46/482). Univariate analysis showed that anterior chamber exudation after PE combined with IOL was related to hypertension history, high myopia, glaucoma, preoperative intraocular pressure > 21mmHg, intraoperative posterior capsular rupture of crystalline body, uveitis, intraoperative pupil diameter < 3mm and lens nucleus grade ≥ grade IV (P<0.05). Multivariate Logistic regression analysis showed that preoperative intraocular pressure > 21mmHg, glaucoma, high myopia, intraoperative posterior capsular rupture of crystalline body, uveitis and lens nucleus grade ≥ IV were the influencing factors of postoperative anterior chamber exudation (P<0.05). Conclusion: PE combined with IOL in the treatment of cataract has good curative effect, can effectively improve the visual acuity of patients, and the incidence of complications is low. Postoperative anterior chamber exudation is affected by many factors. In clinical work, intervention and treatment measures should be formulated according to relevant factors to reduce the risk of postoperative anterior chamber exudation. |