Objective: To improve the diagnosis and treatment of primary uterine malignant lymphoma. Methods: The literature on primary uterine malignant lymphoma reported from January 2001 to August 2018 was searched by PubMed, Wanfang Med Online, VIP date base and China National Knowledge Infrastructure, and combined with a primary disease admitted to Beijing Obstetrics and Gynecology Hospital affiliated to Capital Medical University. Case data of uterine large B-cell lymphoma were summarized, and the clinical manifestations, imaging and pathological features, treatment options and prognosis of these patients were summarized. Results: A 64 years old female, complaint with vaginal bleeding after menopause, pelvic CT prompt: cervical and lower uterine segment was invaded by massive soft tissue, the fund of the uterus and the endometrial was normal. Hysteroscopic biopsy confirmed as primary uterine large B cell lymphoma. Dissection of the whole uterus and bilateral annexes, omentum and retroperitoneal lymph node was done, complied with CHOP chemotherapy postoperatively. Conclusion: Primary uterine malignant lymphoma is extremely rare. Its histopathology mainly consists of B-cell lymphoma with high degree of malignancy. Radical surgery is the main treatment and chemotherapy is supplemented. The prognosis of such diseases is poor. |