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胆囊切除术后急性胰腺炎患者314例发病特点分析 |
Characteristic Analysis of 314 patients with Acute Pancreatitis after Cholecystectomy |
投稿时间:2017-02-05 修订日期:2017-02-11 |
DOI: |
中文关键词: 胆囊切除术 胆源性胰腺炎 高脂血症性胰腺炎 |
英文关键词: Cholecystectomy Biliary Pancreatitis Hyperlipidemic Pancreatitis |
基金项目:重症急性胰腺炎综合救治创新体系关键技术的构建及模式推广,2015SZ0229,四川省科技厅支撑计划项目 |
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中文摘要: |
目的:研究胆囊切除术后患者发生急性胰腺炎的发病特点。方法:回顾性分析2009年10月至2013年10月四川大学华西医院诊断急性胰腺炎且既往行胆囊切除术病史患者的病因分析、病情严重程度、临床特征与转归。结果:研究共纳入314例患者,以高脂血症性胰腺炎占比最高,共110例(35%),胆源性胰腺炎和混合性胰腺炎分别为107例(32%)、96例(31%),酒精性仅7例(2%)。其中轻症215例,中度31例,重度68例,高脂血症性胰腺炎患者重症率(36%)、胰腺及胰周坏死率(28%)、持续性器官功能衰竭率(36%)、呼吸衰竭率(41%)、ICU转入率(26%)高于胆源性组和混合组,并具有统计学差异。(P<0.05)结论:胆囊切除后的急性胰腺炎以胆源性胰腺炎和高脂血症性胰腺炎居多,其中高脂血症性胰腺炎临床表现更严重。 |
英文摘要: |
Objective: to determine the characteristic of patients in acute pancreatitis(AP) after cholecystectomy. Method: Retrospective analysis of etiology, severity, clinical feature of AP patients with the history of cholecystectomy in West China Hospital from 2009.10 to 2013.10. Results: 314 patients were included. Causes included , the most frequent one, hyperlipidemic pancreatitis (110, 35%), biliary pancreatitis (107, 32%), alcoholic pancreatitis (7, 2%), and the mixed-causes pancreatitis(96, 31%). 215 cases were mild AP, 31 cases were moderately severe AP, 68 cases were severe AP. The rate of Severe AP(36%), pancreatic and peripancreatic necrosis(28%), persistent organ failure(36%), respiratory failure(41%), ICU transferring(26%)in hyperlipidemic pancreatitis is significantly higher than biliary pancreatitis and the mixing-causes pancreatitis. Conclusion: biliary pancreatits and hyperlipidemic pancreatitis are dominantly prevalent in AP patients with history of cholecystectomy. And the clinical feature of hyperlipidemic pancreatitis is more severe than that of biliary pancreatitis. |
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