| .急性ST段抬高型心肌梗死患者血清FIB、TG/HDL-C比值、MPV/PC比值与院内新发心房颤动的关系研究[J].,2024,(24):4736-4739 |
| 急性ST段抬高型心肌梗死患者血清FIB、TG/HDL-C比值、MPV/PC比值与院内新发心房颤动的关系研究 |
| Study on the Relationship between Serum FIB, TG/HDL-C Ratio, MPV/PC Ratio and New-onset Atrial Fibrillation in Patients with Acute ST-Segment Elevation Myocardial Infarction |
| 投稿时间：2024-09-09 修订日期：2024-10-12 |
| DOI：10.13241/j.cnki.pmb.2024.24.032 |
| 中文关键词: 急性ST段抬高型心肌梗死 FIB TG/HDL-C比值 MPV/PC比值 新发心房颤动 |
| 英文关键词: Acute ST-segment elevation myocardial infarction FIB TG/HDL-C ratio MPV/PC ratio New-onset atrial fibrillation |
| 基金项目:山东省医药卫生科技发展计划项目（202003011333） |
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| 中文摘要: |
| 摘要 目的：探讨急性ST段抬高型心肌梗死（ASTEMI）患者血清纤维蛋白原（FIB）、三酰甘油/高密度脂蛋白胆固醇（TG/HDL-C）比值、平均血小板体积/血小板计数（MPV/PC）比值与院内新发心房颤动（NOAF）的关系。方法：根据274例ASTEMI患者院内是否发生NOAF将其分为NOAF组（41例）和非NOAF组（233例），检测并对比两组FIB、TG/HDL-C比值、MPV/PC比值。采用多因素Logistic回归分析ASTEMI患者院内发生NOAF的影响因素。结果：NOAF组血清FIB、TG/HDL-C比值、MPV/PC比值高于非NOAF组（P＜0.05）。NOAF组Killip分级≥Ⅱ级比例高于非NOAF组（P＜0.05）。Killip分级≥Ⅱ级、血清FIB、TG/HDL-C比值、MPV/PC比值均升高是ASTEMI患者院内发生NOAF的独立危险因素。结论：ASTEMI患者血清FIB、TG/HDL-C比值、MPV/PC比值均升高，是患者院内发生NOAF的危险因素。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the relationship between serum fibrinogen (FIB), triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio, mean platelet volume/platelet count (MPV/PC) ratio and in-hospital new-onset atrial fibrillation (NOAF) in patients with acute ST-segment elevation myocardial infarction (ASTEMI). Methods: 274 ASTEMI patients were divided into NOAF group (41 cases) and Non NOAF group (233 cases) according to whether NOAF occurred in the hospital, FIB, TG/HDL-C ratio and MPV/PC ratio were detected and compared in two groups. The influencing factors of in-hospital NOAF in ASTEMI patients were analyzed by multivariate Logistic regression. Results: The serum FIB, TG/HDL-C ratio and MPV/PC ratio in NOAF group were higher than those in Non NOAF group (P<0.05). The proportion of Killip grade≥II in NOAF group was higher than that in Non NOAF group (P<0.05). Killip grade≥II, elevated serum FIB, TG/HDL-C ratio, and MPV/PC ratio were independent risk factors for NOAF in ASTEMI patients. Conclusion: The serum FIB, TG/HDL-C ratio and MPV/PC ratio of ASTEMI patients are increased, which are the risk factors of NOAF in patients. |
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