| .肺动脉血栓抽吸术与肺动脉置管溶栓术在中高危肺栓塞患者中的
疗效评价[J].,2024,(24):4689-4691 |
| 肺动脉血栓抽吸术与肺动脉置管溶栓术在中高危肺栓塞患者中的
疗效评价 |
| Comparative Analysis of the Effect of Acostream Catheter for Pulmonary Artery Thrombus Aspiration and Pulmonary Artery Catheterization and Thrombolysis in Patients with Pulmonary Embolism |
| 投稿时间：2024-07-22 修订日期：2024-08-17 |
| DOI：10.13241/j.cnki.pmb.2024.24.019 |
| 中文关键词: Acostream导管 肺动脉血栓抽吸术 肺动脉置管溶栓术 肺栓塞 |
| 英文关键词: Acostream catheter Pulmonary artery thrombus aspiration Pulmonary artery catheter thrombolysis Pulmonary embolism |
| 基金项目:陕西省重点研发计划项目（S2022-YF-ZDCXL-ZDLSF-0140） |
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| 中文摘要: |
| 摘要 目的：探讨Acostream导管行肺动脉血栓抽吸术（ACTA）与肺动脉置管溶栓术（PACT）在中高危肺栓塞（PE）患者中的治疗效果。方法：选取2022.1-2024.3收治的90例中高危PE患者，分为ACTA组和PACT组，各45例。PACT组给予尿激酶肺动脉置管溶栓治疗，ACTA组给予Acostream导管行肺动脉血栓抽吸治疗。比较两组相关指标。结果： (1)ACTA组治疗总有效率高于PACT组（P=0.025）。(2)治疗后，ACTA组右心室大小、TR、PASP、PADP均较PACT组降低（P<0.05）。(3)治疗后，ACTA组与PACT组PaO2较治疗前上升，PaCO2下降，且ACTA组改善幅度大于PACT组（P＜0.05）。两组治疗后血浆BNP和cTnI和D-二聚体水平均低于治疗前，且ACTA组下降更明显（P＜0.05）。(4)ACTA组并发症发生率低于PACT组（P＜0.05）。结论：对急性PE患者实施ACTA，可快速清除栓塞血管内血栓，恢复肺动脉血流，改善血气状态，疗效较优，且并发症风险低，安全性高。 |
| 英文摘要: |
| ABSTRACT Objective: To compare and analyze the application effects of Acostream catheter-directed pulmonary artery thrombus aspiration (ACTA) and pulmonary artery catheter thrombolysis (PACT) in patients with pulmonary embolism(PE). Methods: 90 intermediate and high-risk PE patients admitted to 2022.1-2024.3 were selected and divided into the ACTA group and the PACT group, with 45 patients each. The PACT group was given urokinase pulmonary artery catheterization for thrombolysis, and the ACTA group was given a Acostream catheter for pulmonary artery thrombus aspiration. Compare the two groups of relevant indicators. Results: (1) The total response rate was higher in the ACTA group than in the PACT group (P=0.025). (2) After treatment, the RV size, TR, PASP, and PADP all decreased in the ACTA group compared with the PACT group(P<0.05). (3) After treatment, PaO2 increased in the ACTA and PACT groups compared with PaCO2 decreased before treatment, and the improvement in the ACTA group was greater than that in the PACT group(P<0.05). Plasma BNP and cTnI and D-dimer levels were lower after both treatment than before treatment, and the decrease was more pronounced in the ACTA group(P<0.05). (4) The complication rate was lower in the ACTA group than that in the PACT group (P<0.05). Conclusion: ACTA in patients with acute PE can quickly remove embolic vascular thrombosis, restore pulmonary artery blood flow, improve blood gas status, with excellent efficacy, low risk of complications and high safety. |
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