| 黄 蕾,陈 丽,吴 巧,陈 宇,谭顺林.心率减速力、连续心率减速力及心率加速力与慢性心衰患者预后的相关性[J].,2024,(16):3166-3170 |
| 心率减速力、连续心率减速力及心率加速力与慢性心衰患者预后的相关性 |
| Correlation between DC, DRs, AC and Prognosis in Patients with CHF |
| 投稿时间：2024-02-08 修订日期：2024-02-28 |
| DOI：10.13241/j.cnki.pmb.2024.16.033 |
| 中文关键词: 心率减速力 心率加速力 连续心率减速力 慢性心衰 相关性 |
| 英文关键词: Deceleration capacity of heart rate Acceleration capacity of heart rate Heart rate deceleration runs Chronic heart failure Correlation |
| 基金项目:四川省医学会高血压疾病（施慧达）专项科研课题（2018SHD5-1） |
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| 中文摘要: |
| 摘要 目的：探讨心率减速力（deceleration capacity of heart rate, DC）、连续心率减速力（Heart Rate deceleration runs, DRs）及心率加速力（acceleration capacity of heart rate, AC）与慢性心衰患者（CHF）预后的相关性。方法：将2021年10月至2022年10月我院心内科收治的120例CHF患者纳入观察组，根据心功能分级标准分组：Ⅱ级组、Ⅲ级组、Ⅳ级组各40、50、30例，另纳入69例同期门诊体检健康志愿者为对照组，对比两组一般资料，分析DC、DRs、AC表达情况，并对观察组患者进行为期一年的随访，记录心血管事件发生情况，探讨DC、DRs、AC在心血管事件中的评估价值。结果：观察组DC、DR2、DR4、DR8、LVEF水平均显著低于对照组，LVEDD、AC高于对照组（P＜0.05）；Ⅳ级组DC、DR2、DR4、DR8、LVEF水平均显著低于Ⅲ级组、Ⅱ级组，LVEDD、AC高于Ⅲ级组、Ⅱ级组（P＜0.05）；Ⅲ级组DC、DR2、DR4、DR8、LVEF水平均显著低于Ⅱ级组，LVEDD、AC高于Ⅱ级组（P＜0.05）；事件组DC、DR2、DR4、DR8、LVEF水平均显著低于非事件组，LVEDD、AC高于非事件组（P＜0.05）；高危组恶性心律失常、心力衰竭再次住院、心源性休克、心源性死亡发生率显著高于中危组及低危组（P＜0.05），中危组以上事件发生率亦显著高于低危组（P＜0.05）。结论：DC、DRs、AC在CHF患者心功能分级及预后评估中具有指导意义，临床可通过监测CHF患者以上指标变化情况，为治疗及预防心血管事件发生提供客观依据。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the correlation between DC, DRs, AC and prognosis in patients with CHF. Methods: 120 patients with CHF (observation group) admitted to cardiology department of the hospital from October 2021 to October 2022 were divided into grade II group (n=40), grade III group (n=50), and grade IV group (n=30) based on cardiac function classification. 69 healthy volunteers who received physical examination in the hospital during the same period were selected as the control group. General data of the two groups were compared. DC, DRs and AC were analyzed. Patients in the observation group were followed up for one year, and cardiovascular events were recorded. The value of DC, DRs and AC in evaluating cardiovascular events was discussed. Results: Comparison between the observation group and the control group found that DC, DR2, DR4, DR8 and LVEF of the former group were lower. LVEDD and AC of the former group were greater(P<0.05). As the grade of cardiac function increased, DC, DR2, DR4, DR8 and LVEF decreased. LVEDD and AC increased(P<0.05). Comparison between the event group and the non-event group found that DC, DR2, DR4, DR8 and LVEF in the former group were lower. LVEDD and AC in the former group were greater (P<0.05). The occurrence rates of malignant arrhythmia, readmission due to heart failure, cardiogenic shock, and cardiogenic death were higher in the high-risk group than in the intermediate-risk group and the low-risk group(P<0.05), and higher in the intermediate-risk group than in the low-risk group (P<0.05). Conclusion: DC, DRs and AC are of guiding significance in cardiac function classification and prognosis evaluation of patients with CHF. Clinically, monitoring the changes in above indicators in patients with CHF can provide an objective basis for the treatment and prevention of cardiovascular events. |
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