| Objective: To investigate the characteristics of pathogenic bacteria of biliary tract infection after endoscopic retrograde cholangiopancreatography (ERCP) lithotomy, and to analyze its risk factors. Methods: 256 choledocholithiasis patients who were admitted in our hospital from April 2020 to October 2023 were selected, patients were divided into infection group (n=31) and non-infection group (n=225) according to whether biliary tract infection occurred after ERCP lithotomy. The characteristics of pathogenic bacteria of biliary tract infection after ERCP lithotomy between the two groups were analyzed, and the risk factors of biliary tract infection were analyzed. Results: Among 256 cholangiolithiasis patients, the incidence of biliary tract infection was 12.11% (31/256). A total of 39 strains of pathogenic bacteria were isolated from 31 patients with biliary tract infection after ERCP, 26 strains were mainly gram-negative bacteria, accounting for 66.67%. Next was gram-positive bacteria, with 10 strains, accounting for 25.64%. Finally, there were 3 strains of fungi, accounting for 7.69%. The proportion of age ≥ 60 years old, the proportion of previous history of biliary tract surgery, the proportion of stone number ≥2, the proportion of sphincter of Oddi dysfunction, the proportion of diabetes, the proportion of obstruction of postoperative biliary drainage, the operation time and the preoperative TBil level in infection group were higher than those in non-infection group (P<0.05). Combined age ≥60 years old, previous history of biliary tract surgery, stone number ≥ 2, long operation time, diabetes, and obstruction of postoperative biliary drainage were risk factors for biliary tract infection (P<0.05). Conclusion: Gram-negative bacteria are the main pathogens of biliary tract infection in patients with choledocholithiasis after ERCP. Combined age ≥ 60 years old, previous history of biliary tract surgery, stone number≥ 2, long operation time, diabetes, and obstruction of postoperative biliary drainage are risk factors for biliary tract infection after ERCP lithotomy. |
