文章摘要
2019-2023年珠海市香洲区初治痰涂阳肺结核患者流行病学特征及影响因素的Logistic回归预测模型建立
A Logistic regression prediction model of the epidemiological characteristics and influencing factors of patients with primary sputum smear positive tuberculosis in Xiangzhou District, Zhuhai city, 2019-2023
投稿时间:2024-10-23  修订日期:2024-10-23
DOI:
中文关键词: 初治肺结核  流行病学特征  强化期痰转阴  影响因素  预测模型
英文关键词: primary treatment of tuberculosis  epidemiological characteristics  strengthening sputum turning negative  influencing factors and prediction model
基金项目:
作者单位邮编
江澄瑜 中山大学公共卫生学院 510080
张定梅* 中山大学公共卫生学院 510080
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中文摘要:
      【目的】调查2019-2023年珠海市香洲区初治痰涂阳肺结核患者流行病学特征,及构建影响因素的Logistic回归预测模型,为该地的结核病防治策略的制定提供参考。【方法】应用描述性研究及logistics回归分析方法,通过“中国疾病预防控制信息系统”收集资料,对患者特征及影响强化期痰转阴的因素进行分析,构建Log P回归预测模型,分析其预测效能。【结果】筛选初治痰涂阳肺结核患者1005例,强化期痰转阴率为91%,男女性别构成比为1.8:1,45-64岁年龄段、家务及待业职业、省间流动、追踪发现、夏季6月份发病的患者占比最多。多因素logistic回归分析显示,性别为男、45~64岁年龄段、春季发病为强化期痰未转阴的危险因素。对应的回归预测模型,经ROC分析可知:该预测模型有较好的对痰转阴的预测效能,其ROC-AUC(0.95CI)为0.728(0.631~0.825),预测敏感度为82%,准确度为67%。【结论】珠海市香洲区要注重男性、青中年、省间流动、家务及待业人群、夏季尤其6月份的肺结核发病群体,男性、青中年、春季发病增加强化期痰涂片转阴失败的风险,通过影响因素构建的预测模型对肺结核痰转阴有较好的预测效能。应加强重点人群及时期的健康宣传教育工作,针对性的制定结核疫情防控的措施策略,促进痰菌转阴,减少疾病的传播。
英文摘要:
      [Objective] Investigate the epidemiological characteristics of patients with primary sputum smear positive tuberculosis in Xiangzhou District, Zhuhai city from 2019 to 2023, and construct a Logistic regression prediction model of influencing factors to provide reference for the formulation of tuberculosis control strategies in this area.[Methods] Descriptive research and logistics regression analysis were used to collect data through "China Disease Prevention and Control Information System", analyze patient characteristics and factors affecting the sputum turning Yin in the strengthening period, and build a LogP regression prediction model to analyze its prediction efficacy.[Results] 1005 patients with pulmonary tuberculosis were selected, and the rate of sputum conversion was 91%, and the gender composition ratio was 1.8:1. The proportion of patients aged 45-64 years, housework and unemployed occupation, inter-provincial mobility, tracking discovery, and the onset in summer accounted for the most. Multivariate logistic regression analysis showed that gender was male, 45 to 64 years, and spring onset were risk factors for sputum conversion in the enhanced period. According to the corresponding regression prediction model, according to ROC analysis, the prediction model has a good prediction efficiency for sputum to Yin, and its ROC-AUC(0.95CI) is 0.728 (0.631~0.825), the prediction sensitivity is 82%, and the accuracy is 67%.[Conclusion] Zhuhai xiangzhou district should pay attention to male, green middle-aged, flow between provinces, housework and unemployed people, summer, especially tuberculosis group in June, male, green middle-aged, spring increased intensive sputum smear to Yin risk of failure, through the influence factors to build the prediction model of tuberculosis sputum to Yin have good prediction efficiency. Health publicity and education for key groups and periods should be strengthened, and targeted measures for tuberculosis epidemic prevention and control should be formulated to promote sputum bacteria and reduce the spread of diseases.
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