| 刘贝贝,袁 畅,邹 琴,李 凤,陈金艳.消肿溃痈方联合湿润烧伤膏对肛周脓肿术后患者创面愈合效果、肛门功能和血清生长因子的影响[J].,2024,(10):1965-1968 |
| 消肿溃痈方联合湿润烧伤膏对肛周脓肿术后患者创面愈合效果、肛门功能和血清生长因子的影响 |
| Effect of Xiaozhong Kuiyong Formula Combined with Moist Exposed Burn Ointment on Wound Healing Effect, Anal Function, and Serum Growth Factor in Postoperative Patients with Perianal Abscess |
| 投稿时间：2023-10-08 修订日期：2023-10-23 |
| DOI：10.13241/j.cnki.pmb.2024.10.034 |
| 中文关键词: 消肿溃痈方 湿润烧伤膏 肛周脓肿术 创面愈合 肛门功能 血清生长因子 |
| 英文关键词: Xiaozhong Kuiyong formula Moist exposed burn ointment Perianal abscess surgery Wound healing Anal function Serum growth factor |
| 基金项目:湖南省卫生健康委科研立项课题（20200338） |
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| 中文摘要: |
| 摘要 目的：观察消肿溃痈方联合湿润烧伤膏对肛周脓肿术后患者创面愈合效果、肛门功能和血清生长因子的影响。方法：按照双色球法，将2020年5月~2022年12月期间湖南中医药大学第一附属医院收治的120例肛周脓肿术后患者分为对照组（n=60，接受湿润烧伤膏治疗）和观察组（n=60，消肿溃痈方联合湿润烧伤膏治疗）。对比两组疗效、临床指标、肛门功能指标、血清生长因子指标。结果：与对照组相比，观察组的临床总有效率更高（P<0.05）。与对照组相比，观察组的疼痛消失时间、肿胀消失时间、住院时间和创面愈合时间更短（P<0.05）。与对照组相比，观察组治疗3个疗程后肛管静息压、肛管最大收缩压、直肠最大耐受阈值更高（P<0.05）。与对照组相比，观察组治疗3个疗程后碱性成纤维细胞生长因子（bFGF）、酸性成纤维细胞生长因子（aFGF）更高（P<0.05）。结论：消肿溃痈方联合湿润烧伤膏可促进肛周脓肿术后患者创面愈合，改善患者的肛门功能，促进血清生长因子分泌。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the effect of Xiaozhong Kuiyong formula combined with moist exposed burn ointment on wound healing effect, anal function, and serum growth factor in postoperative patients with perianal abscess. Methods: According to the bicolor sphere method, 120 postoperative patients with perianal abscesses admitted to the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine from May 2020 to December 2022 were divided into control group (n=60, treated with moist exposed burn ointment) and observation group (n=60, treated with Xiaozhong Kuichuan formula combined with moist exposed burn ointment). The efficacy, clinical indicators, anal function indicators, and serum growth factor indicators of the two groups were compared. Results: Compared with the control group, the clinical total effective rate of the observation group was higher (P<0.05). Compared with the control group, the pain disappearance time, swelling disappearance time, hospitalization time, and wound healing time of the observation group were shorter (P<0.05). Compared with the control group, the anal resting pressure, anal maximum systolic pressure, and rectal maximum tolerance threshold at 3 courses after treatment of the observation group were higher (P<0.05). Compared with the control group, the levels of basic fibroblast growth factor(bFGF) and acidic fibroblast growth factor (aFGF) at 3 courses after treatment of the observation group were higher(P<0.05). Conclusion: Xiaozhong Kuiyong formula combined with moist exposed burn ointment could promote wound healing, improve anal function, and promote serum growth factor secretion in postoperative patients with perianal abscess. |
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